99474-17-6Relevant articles and documents
Synthesis of 3--5-indolecarboxylic Acid, an Antihypertensive Agent with a Novel Mode of Action
Boettcher, Henning,Gericke, Rolf
, p. 749 - 752 (2007/10/02)
The pharmacologically active title compound 1c is prepared in a straightforward six-stage synthesis.The intermediate 4 is obtained by Leimgruber-Batcho indole synthesis.The 3-alkyl side chain is introduced by Friedel-Crafts acylation with 4-chlorobutyryl