99646-81-8

Basic information

• Product Name: Benzaldehyde, 2-amino-6-methyl-
• Synonyms: Benzaldehyde, 2-amino-6-methyl-;2-amino-6-methylbenzaldehyde
• CAS NO: 99646-81-8
• Molecular Formula: C8H9NO
• Molecular Weight: 135.16316
• Mol File: 99646-81-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzaldehyde, 2-amino-6-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-amino-6-methyl-(99646-81-8)
• EPA Substance Registry System: Benzaldehyde, 2-amino-6-methyl-(99646-81-8)

Safety Data

• Hazardous Substances Data: 99646-81-8(Hazardous Substances Data)

Usage

General Description

Benzaldehyde, 2-amino-6-methyl- is a chemical compound with the molecular formula C8H9NO. It is a derivative of benzaldehyde and contains an amino group and a methyl group attached to the benzene ring. Benzaldehyde, 2-amino-6-methyl- is commonly used as a fragrance and flavoring agent in the production of various consumer products, including perfumes, soaps, and food items. It also has potential applications in the pharmaceutical industry, where it can be used as an intermediate in the synthesis of various drugs. Additionally, it has been studied for its potential health effects, including its role as a mutagen and its potential use in cancer treatment.

Upstream product

• 65658-16-4 2-amino-6-methylbenzyl alcohol 
• 4389-50-8 2-amino-6-methylbenzoic acid 
• 61940-22-5 methyl 2-methyl-6-nitrobenzoate 
• 13506-76-8 2-methyl-6-nitrobenzoic acid 
• 54915-41-2 2-(hydroxymethyl)-3-methyl-1-nitrobenzene 

Relevant articles and documents

Easy Access to Quinolin-2(1 H)-ones via a One-Pot Tandem Oxa-Michael-Aldol Sequence

An efficient strategy for the synthesis of a variety of quinolin-2(1 H)-one derivatives has been developed. The reaction proceeded from cinnamide derivatives via a tandem reaction in the presence of NaOH to afford the corresponding 2- quinolin-2(1 H)-one derivatives in good to excellent yields.

Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands

We have reported previously the novel δ opioid agonist KNT-127 which showed high affinity and selectivity for the δ receptor. Moreover, the analgesic effect of subcutaneously administered KNT-127 was more potent than that of a prototypical δ agonist (-)-TAN-67 in the acetic acid writhing test. This study of the structure-activity relationship of KNT-127 derivatives focused on the introduction of substituents onto the 5′-, 6′-, 7′- or 8′-position of the quinoline ring and revealed that many derivatives with 5′- or 8′-substituents showed high affinities and selectivities for the δ receptor. Especially, SYK-153 with an 8′-OH group showed the highest affinity and the most balanced and highest selectivity for the δ receptor among the synthesized compounds.