1245566-29-3Relevant articles and documents
Process for the preparation of triiodinated carboxylic aromatic derivatives
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Page/Page column 8; 9, (2010/10/03)
The present invention relates to a process for the preparation of given carboxamido compounds, in particular of 2,4,6-triiodoisophthalic acid derivatives, as useful intermediates for the preparation of X-ray contrast media among which is iopamidol. The said process comprises reacting suitable N-sulfinyl intermediate compounds with a commercially available α-hydroxyacid or a salt thereof.