Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Calcium pantothenate
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

Calcium pantothenate

 EINECS 205-278-9
CAS No. 137-08-6 Density 1.266 g/cm3
PSA 191.72000 LogP -1.45900
Solubility water: 50 mg/mL at 25 °C, clear, nearly colorless Melting Point 190 °C
Formula C18H32CaN2O10 Boiling Point 551.5 °C at 760 mmHg
Molecular Weight 476.537 Flash Point 287.3 °C
Transport Information 25kgs Appearance white crystalline powder
Safety 24/25-45-36/37/39-26-22 Risk Codes 20/21/22-37/38-41-48
Molecular Structure Molecular Structure of 137-08-6 (D-(+)-Pantothenic acid calcium salt) Hazard Symbols HarmfulXn
Synonyms

b-Alanine,N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-;(+)-Pantothenic acid calcium salt;Calcium D-(+)-N-(a,g-dihydroxy-b,b-dimethylbutyryl)-b-alaninate;Calcium D-(+)-pantothenate;Calcium D-pantothenate;b-Alanine,N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-, calcium salt (2:1);Calpan;Calpanate;Dextro calcium pantothenate;N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-b-alanine calcium;NSC 36292;Pancal;Panthoject;Pantholin;Pantothenate calcium;Pantothenicacid calcium salt;Pantothenic acid hemicalcium salt;Vitamin B5 calcium salt;D-Calcium Pantothenate;Calcium,bis(pantothenato)- (7CI);Pantothenic acid, calcium salt (2:1), D- (8CI);

Article Data 9

Calcium pantothenate Synthetic route

176374-84-8

D-pantolactone

36321-40-1

calcium beta-alaninate

137-08-6

calcium (R)-pantothenate

Conditions
ConditionsYield
Stage #1: calcium beta-alaninate In ethanol at 75℃; for 6h;
Stage #2: D-pantolactone In ethanol at 75℃; for 16h; Temperature;		96%
36321-40-1

calcium beta-alaninate

599-04-2

(R)-Pantolacton

137-08-6

calcium (R)-pantothenate

Conditions
ConditionsYield
With sodium chloride; calcium oxide Reagent/catalyst; Milling;71%
Stage #1: (R)-Pantolacton In methanol for 1h; Heating; Large scale; Green chemistry;
Stage #2: calcium beta-alaninate In methanol for 2h; Reflux; Large scale; Green chemistry;
16690-93-0

sodium β-alaninate

599-04-2

(R)-Pantolacton

A

calcium pantoate

B

calcium panto-β-alanyl-β-alaninate

C

137-08-6

calcium (R)-pantothenate

Conditions
ConditionsYield
In methanol Product distribution / selectivity;
137-08-6, 867-80-1, 6381-62-0, 6381-63-1, 15773-29-2, 64789-49-7, 122484-60-0, 131346-21-9

calcium-N-(2,4-dihydroxy-3,3-dimethylbutyryl)-β-alaninate

A

137-08-6

calcium (R)-pantothenate

B

137-08-6, 867-80-1, 6381-62-0, 6381-63-1, 15773-29-2, 64789-49-7, 122484-60-0, 131346-21-9

calcium (S)-pantothenate

Conditions
ConditionsYield
In methanol; water at 35℃; Resolution of racemate;
137-08-6

calcium (R)-pantothenate

79-83-4

pantothenic acid

Conditions
ConditionsYield
With oxalic acid In water at 20℃; for 2h;95.11%
With (1S)-10-camphorsulfonic acid; trifluoroacetic acid at 0℃;
With Amberlite IR-120 In water Inert atmosphere;
With oxalic acid In water at 20℃; for 2h;
137-08-6

calcium (R)-pantothenate

67-63-0

isopropyl alcohol

131205-05-5

(R)-isopropyl 3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate

Conditions
ConditionsYield
With hydrogenchloride In water at 0 - 20℃; Reflux;90%
2186-92-7

p-Anisaldehyde dimethyl acetal

137-08-6

calcium (R)-pantothenate

864239-47-4

3-{[(4R)-2-(p-methoxyphenyl)-5,5-dimethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid

Conditions
ConditionsYield
Stage #1: calcium (R)-pantothenate With sulfuric acid In N,N-dimethyl-formamide for 1h; Inert atmosphere;
Stage #2: p-Anisaldehyde dimethyl acetal In N,N-dimethyl-formamide for 16h; Inert atmosphere;		75%
Stage #1: calcium (R)-pantothenate With sulfuric acid In acetone at 20℃; for 2h;
Stage #2: p-Anisaldehyde dimethyl acetal With toluene-4-sulfonic acid In acetone at 20℃; for 37h;		34%
137-08-6

calcium (R)-pantothenate

67-64-1

acetone

167308-62-5

3-{[(4R)-2,2,5,5-tetramethyl-1,3-dioxan-4-yl]carbonylamino}propionic acid

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20℃; for 16h; Inert atmosphere; Molecular sieve;73%
With toluene-4-sulfonic acid at 20℃; for 18h; Molecular sieve;55%
With toluene-4-sulfonic acid at 20℃; Molecular sieve;36.8%
17612-91-8

1-[(2-aminoethyl)sulfanyl]ethan-1-one hydrochloride

137-08-6

calcium (R)-pantothenate

6098-36-8

(R)-S-(2-(3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanamido)ethyl) ethanethioate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N,N-tetramethyluroniumhexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h;73%
1256166-26-3

(E)-4-(phenylsulfonyl)but-3-en-1-amine hydrochloride

137-08-6

calcium (R)-pantothenate

1245941-20-1

(R,E)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-(4-(phenylsulfonyl)but-3-enylamino)propyl)-butanamide

Conditions
ConditionsYield
With N-ethylmorpholine;; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃;64%

Calcium pantothenate Chemical Properties

IUPAC Name: calcium 3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propanoate 
Empirical Formula: C18H32CaN2O10
Molecular Weight: 476.5321g/mol
EINECS: 205-278-9 
Structure of Calcium pantothenate (CAS NO.137-08-6):

Melting Point: 190 °C
Flash Point: 287.3 °C
Enthalpy of Vaporization: 95.61 kJ/mol
Boiling Point: 551.5 °C at 760 mmHg
Vapour Pressure: 1.84E-14 mmHg at 25°C 
Solubility: H2O: 50 mg/mL at 25 °C, clear, nearly colorless
Stability: Stable, but may be moisture or air sensitive. Incompatible with strong acids, strong bases. 
Product Categories: Biochemistry;Ca (Calcium) Compounds;Classes of Metal Compounds;Typical Metal Compounds;Vitamins;Nutritional Supplements;Nutritional fortification substances 
Canonical SMILES: CC(C)(CO)C(C(=O)NCCC(=O)[O-])O.CC(C)(CO)C(C(=O)NCCC(=O)[O-])O.[Ca+2]
InChI: InChI=1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2
InChIKey: FAPWYRCQGJNNSJ-UHFFFAOYSA-L

Calcium pantothenate Uses

 Calcium Pantothenate is used as extender of Nutrition in animal feed.

Calcium pantothenate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 920mg/kg (920mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
mouse LD50 intravenous 910mg/kg (910mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
mouse LD50 oral 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 599, 1982.
mouse LD50 subcutaneous 2700mg/kg (2700mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
rat LD50 intraperitoneal 820mg/kg (820mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
rat LD50 intravenous 830mg/kg (830mg/kg)   Drugs in Japan Vol. 6, Pg. 599, 1982.
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 599, 1982.
rat LD50 subcutaneous 3400mg/kg (3400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940

RTECS  RU4375000

Calcium pantothenate Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 20/21/22-37/38-41-48 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes. 
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 24/25-45-36/37/39-26-22
S24/25:Avoid contact with skin and eyes. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S22:Do not breathe dust.
WGK Germany: 1
RTECS: RU4375000
F: 3-10

Calcium pantothenate Specification

  Calcium pantothenate , its cas register number is 137-08-6. It also can be called Bis(pantothenato)calcium ; Ca-HOPA ;
 Calcii pantothenas ; Calcium D-pantothenate ; Calcium d-pantothenate ; Calcium, bis(pantothenato)- ; D-Calcium pantothenate calcium chloride double salt ; Dextro calcium pantothenate ; N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine calcium ; Pancal ; Panthoject ; Pantotenato calcico ; Pantothenate calcium ; Pantothenate de calcium ; Pantothenic acid, calcium salt ; Vitamin B5, calcium salt ; beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)- . Calcium pantothenate (CAS NO.137-08-6) is a white crystalline powder.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 137-08-6