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Croton oil

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Name

Croton oil

EINECS 310-127-6
CAS No. 8001-28-3 Density 0.94 g/mL at 25 °C(lit.)
PSA 0.00000 LogP 0.00000
Solubility Soluble in alcohol, chloroform, ether, and petroleum ether. Insoluble in water. Melting Point N/A
Formula Unspecified Boiling Point N/A
Molecular Weight 0 Flash Point 74 °C
Transport Information N/A Appearance N/A
Safety 23-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 8001-28-3 (CROTON OIL) Hazard Symbols N/A
Synonyms

Croton oil;CCRIS 648;Croton resin;Croton tiglium L. oil;Crotonoel;Crotonoel [German];Oils, croton;Oleum tiglii;

 

Croton oil Consensus Reports

Reported in EPA TSCA Inventory.

Croton oil Specification

The Croton oil, with the CAS registry number 8001-28-3,is also known as Croton tiglia seed oil; Croton tiglium seed oil. It belongs to the product categories of Biochemicals and Reagents;Lipids;Oils. Its chemical's molecular formula is Unspecified. What's more,Its systematic name is Croton oil.It is a colorless liquid with an unpleasant odor which is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality. It is toxic and a strong skin irritant.When you use it,do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) and avoid contact with skin and eyes .

The toxicity data of Croton oil are as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LD50 intraperitoneal 60mg/kg (60mg/kg)   Zeitschrift fuer Krebsforschung. Vol. 65, Pg. 325, 1963.
frog LD50 parenteral 60mg/kg (60mg/kg)   Zeitschrift fuer Krebsforschung. Vol. 65, Pg. 325, 1963.
mouse LD70 subcutaneous 3740ug/kg (3.74mg/kg)   Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 7, Pg. 1276, 1961.
mouse LDLo intraperitoneal 1mg/kg (1mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.

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