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Name	DL-Homatropine hydrobromide	EINECS	200-105-3
CAS No.	51-56-9	Density	1.21g/cm³
PSA	49.77000	LogP	2.78440
Solubility	Soluble in water	Melting Point	214-217 ºC
Formula	C16H21 N O3 . Br H	Boiling Point	434.9 °C at 760 mmHg
Molecular Weight	356.26	Flash Point	216.8 °C
Transport Information	N/A	Appearance	Colorless or white powder. Bromine-like odor.
Safety	Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NO_x and Br⁻.	Risk Codes	R23/24/25
Molecular Structure		Hazard Symbols
Synonyms	1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide (8CI); Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (9CI);Benzeneacetic acid, a-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide,endo-; (?à)-Homatropine bromide;Homatropine bromide; Homatropine hydrobromide; Isopto Homatropine; Mandelicacid tropine ester hydrobromide

DL-Homatropine hydrobromide Chemical Properties

Product Name: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
The MF of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is C₁₆H₂₂BrNO₃.

The MW of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is 356.25.
Synonyms: alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide ; MANDELYTROPINE HYDROBROMIDE ; (+/-)-HOMATROPINE HYDROBROMIDE ; HOMATROPINE HYDROBROMIDE ; DL-HOMATROPINE HYDROBROMIDE ; (+-)-homatropinebromide ; 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide ; alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste
Product Categories: Miscellaneous Natural Products;Alkaloids;Biochemistry;Tropane Alkaloids;Acetylcholine receptor
EINECS: 200-105-3
Form: white crystals or crystalline powder
Flash Point: 197.7 °C
Boiling Point: 403.3 °C at 760 mmHg
Melting Point: 214-217 °C
Water Solubility: soluble
Merck: 4730

DL-Homatropine hydrobromide Uses

Alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9) is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly.

DL-Homatropine hydrobromide Toxicity Data With Reference

1.		ipr-rat LD50:154 mg/kg		DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),789.
2.		ivn-mus LD50:107 mg/kg		JPETAB Journal of Pharmacology and Experimental Therapeutics. 96 (1949),1.

DL-Homatropine hydrobromide Consensus Reports

Reported in EPA TSCA Inventory.

DL-Homatropine hydrobromide Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NO_x and Br⁻.
Safety information of alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide (51-56-9):
Hazard Codes T
Risk Statements 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
Safety Statements 45-24/25-22
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
S24/25: Avoid contact with skin and eyes
S22: Do not breathe dust
RIDADR 1544
RTECS YM5602000

DL-Homatropine hydrobromide Specification

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

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