Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Dexamethasone 17,21-dipropionate

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Dexamethasone 17,21-dipropionate

EINECS
CAS No. 55541-30-5 Density 1.1481 (estimate)
PSA LogP
Solubility Melting Point approximate 205℃
Formula C28H37 F O7 Boiling Point 603.2±55.0 °C(Predicted)
Molecular Weight 504.65 Flash Point
Transport Information Appearance
Safety Poison by subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F. Risk Codes
Molecular Structure Molecular Structure of 55541-30-5 (Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16a)-) Hazard Symbols
Synonyms

Dexamethasone17,21-dipropionate; Dexamethasone dipropionate; Methaderm; ST 12; THS 101

 

Dexamethasone 17,21-dipropionate Chemical Properties

Empirical Formula: C28H37FO7
Molecular Weight: 504.5876 
Index of Refraction: 1.549
Density: 1.24 g/cm3
Flash Point: 318.6 °C
Enthalpy of Vaporization: 102.93 kJ/mol
Boiling Point: 603.2 °C at 760 mmHg
Vapour Pressure: 4.58E-17 mmHg at 25 °C
Product categories of Dexamethasone 17,21-dipropionate (CAS NO.55541-30-5): Anti-inflammatory;Hormone
Structure of Dexamethasone 17,21-dipropionate (CAS NO.55541-30-5):
                    
XLogP3: 3.6
H-Bond Donor: 1
H-Bond Acceptor: 8 
IUPAC Name of Dexamethasone 17,21-dipropionate (CAS NO.55541-30-5): [(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Canonical SMILES: CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC

Dexamethasone 17,21-dipropionate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 276mg/kg (276mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987.
mouse LD50 subcutaneous 183mg/kg (183mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987.
rabbit LD50 subcutaneous 7600ug/kg (7.6mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LD50 intraperitoneal 36500ug/kg (36.5mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LD50 subcutaneous 26mg/kg (26mg/kg) SENSE ORGANS AND SPECIAL SENSES: ACRIMATION: EYE
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LDLo oral 4gm/kg (4000mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.

Dexamethasone 17,21-dipropionate Safety Profile

Poison by subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F.

Dexamethasone 17,21-dipropionate Specification

 Dexamethasone 17,21-dipropionate ,its cas register number is 55541-30-5. It also can be called Dexamethasone dipropionate ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16alpha)- and 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate) .

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields