The recording, coding, storage, and retrieval of chemical information. Early methods involved the use of punched-card systems, of which there were several types. The advent of digital computers made it possible to store and retrieve such data as molecular structure, physical and chemical properties, and other relevant facts with much greater efficiency. The state of the art in chemical documentation is the sophisticated and extensive information bank assembled by Chemical Abstracts Service, a division of ACS. It features on-line call-up and display of the most complex organic formulas and property data for morew than 12 million compounds. Personal computers are used for laboratory instrument control, data collection, and analysis.