Hudson Isorotation Rules

Name:
Hudson Isorotation Rules
Detailed information:
For anomeric (α and β) sugars, Hudson's isorotation rule states that (1) the rotation of carbon 1 in many sugar derivatives is affected in only a minor degree by changes in the structure of the rest of the molecule and (2) changes in the structure of carbon 1 affect in only a minor degree the rotation of the remainder of the molecule. Another way of stating the rule is to say that the rotation of any aldose derivative is the algebraic sum of A and B, where A is the contribution of the anomeric center and B is the contribution of the rest of the molecule.