Malonic Ester Synthesis

Name:
Malonic Ester Synthesis
Detailed information:
Syntheses based on the strongly activated methylene group of malonic esters which on reaction with sodium ethoxide form a resonance-stabilized ion that can be alkylated and acylated. After hydrolysis, the free alkylmalonic acids readily decarboxylate to mono- or disubstituted monocarboxylic acids.