A fundamental generalization concerning the energy relationships of electrons within the atom, namely that no two electrons in the same atom have the same value for all four quantum numbers; corollary to this is the fact that only two electrons can occupy the same orbital, in which case they have opposite spins, i.e., +1/2 and −1/2. This principle has an important bearing on the sequence of elements in the periodic table and on the limiting numbers of electrons in the shells (2 in the first, 8 in the second, 18 in the third, 32 in the fourth, etc.).See Quantum Number; Shell; Orbital Theory.