(1926– ). An American born in Brooklyn, New York who won the Nobel Prize for chemistry in 2004 for his pioneering work concerning the discovery of ubiquitin-mediated protein degradation. Rose received his B.S. in 1948 from Washington State University and his Ph.D. in biochemistry in 1952 from the University of Chicago. He is currently a distinguished professor-in-residence at the Department of Physiology and Biophysics of the College of Medicine at the University of California, Irvine.