A chemical entity (almost invariably radioactive and usually an isotope) added to the reacting elements or compounds in a chemical process, which can be traced through the process by appropriate detection methods, e.g., Geiger counter. Compounds containing tracers are often said to be “tagged” or “labeled.” Carbon-14 is a commonly used tracer, and radioactive forms of iodine and sodium are also used. Many complex biochemical reactions have been examined in this way (e.g., photosynthesis). Nonradioactive deuterium (hydrogen isotope) is sometimes used, the detection being by molecular weight determination. Radioactive enzymes are also available for tracer studies, e.g., ribonuclease, pepsin, trypsin, and others.See Labeling (2).