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Volhard-Erdmann Cyclization

    Name:
    Volhard-Erdmann Cyclization
    Detailed information:
    Synthesis of alkyl and aryl thiophenes by cyclization of disodium succinate or other 1,4-difunctional compounds (γ-oxo acids, 1,4-diketones, chloroacetyl-substituted esters) with phosphorus heptasulfide.
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