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Difenidol hydrochloride

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Difenidol hydrochloride

EINECS 221-850-0
CAS No. 3254-89-5 Density
PSA 23.47000 LogP 4.12650
Solubility Melting Point 212-214°
Formula C21H27NO.HCl Boiling Point 473.3 °C at 760 mmHg
Molecular Weight 345.91 Flash Point 233.5 °C
Transport Information Appearance crystals, soluble in methanol, water
Safety 36 Risk Codes 20/21/22
Molecular Structure Molecular Structure of 3254-89-5 (1-Piperidinebutanol, a,a-diphenyl-, hydrochloride (1:1)) Hazard Symbols Xn
Synonyms

Ansmin;Cefadol;Celmidol;Difenidolin;Maniol;Mecalmin;Pineroro;SKF 478A;Satanolon;Tenesdol;Vontrol;Wansar;

 

Difenidol hydrochloride Chemical Properties

CEFADOL 's Molecular Formula: C21H27NO.HCl
CEFADOL 's Molecular Weight: 345.91
EINECS: 221-850-0  
Synonyms: Difenidol hydrochloride;1,1-Diphenyl-4-(1-piperidyl)butan-1-ol hydrochloride

Difenidol hydrochloride Uses

CEFADOL is used as antiemetic.

Difenidol hydrochloride Toxicity Data With Reference

1.   

orl-rat LD50:515 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
2.   

ipr-rat LD50:82 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
3.   

scu-rat LD50:670 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
4.   

ivn-rat LD50:29 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
5.   

ims-rat LD50:635 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
6.   

orl-mus LD50:400 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
7.   

ipr-mus LD50:105 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
8.   

scu-mus LD50:163 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.
9.   

ivn-mus LD50:37 mg/kg

   IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 4 (1973),193.

Difenidol hydrochloride Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by intramuscular route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

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