- Dimethyl ( )-2,3-O-Isopropylidene-D-tartrate
- Dimethyl ((1-methyl-5-nitro-1H-imidazol-2-yl)methylene)propanedioate
- Dimethyl (2-oxo-3,3-difluoroheptyl)phosphonate
- Dimethyl (2-oxo-4-phenylbutyl)phosphonate
- Dimethyl (2-oxoheptyl)phosphonate
- Dimethyl (2S, 2'S)-1, 1'-((2S, 2'S)-2, 2'-(4, 4'-(biphenyl-4, 4'-diyl)bis(1H-imidazole-4, 2-diyl))bis(pyrrolidine-2, 1-diyl))bis(3-methyl-1-oxobutane-2, 1-diyl)dicarbamate
- Dimethyl (3-phenoxy-2-oxopropyl)phosphonate
- Dimethyl (R)-(+)-methylsuccinate
- Dimethyl (S)-3-hydroxy-L-aspartate
- Dimethyl [2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]malonate
- 76-24-4[5,5'-Bipyrimidine]-2,2',4,4',6,6'(1H,1'H,3H,3'H,5H,5'H)-hexone,5,5'-dihydroxy-
- 762-49-2Ethane,1-bromo-2-fluoro- (6CI,7CI,8CI,9CI)
- 7625-01-64H-1,4-Benzothiazine-2-carboxylicacid, 3-methyl-, ethyl ester
- 76253-77-52-CHLORMETHYL-6-NITRO-QUINOLINE
- 76-25-5Aristocort acetonide
- 76258-20-3Dimethyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
- 76259-00-2Imidazo[1,5-a]pyridine-3(2H)-thione
- 76260-78-1Substance P,11-L-methionine-, methyl ester
- 76263-11-14-Benzothiazolecarboxylicacid, 2-amino-4,5,6,7-tetrahydro-, ethyl ester
- 76263-18-8Azetidine,3-phenoxy-
Hot Products
- 1010-60-22-Chloro-1,4-naphthoquinone
- 123-06-8Ethoxymethylenemalononitrile
- 437-74-1Xanthinol nicotinate
- 58108-05-7Cyclopenta[c]pyrrol-2(1H)-amine,hexahydro-, hydrochloride (1:1)
- 95-88-54-Chlororesorcinol
- 7439-92-1Lead
- 19766-89-3Hexanoic acid,2-ethyl-, sodium salt (1:1)
- 95-45-4Dimethylglyoxime
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Dimethyl acetylenedicarboxylate |
EINECS | 212-098-4 |
| CAS No. | 762-42-5 | Density | 1.206 g/cm3 |
| PSA | 52.60000 | LogP | -0.66420 |
| Solubility | Soluble in most organic solvents. Insoluble in water. | Melting Point |
-18 °C |
| Formula | C6H6O4 | Boiling Point | 204.309 °C at 760 mmHg |
| Molecular Weight | 142.111 | Flash Point | 86.111 °C |
| Transport Information | UN 3265 8/PG 2 | Appearance | clear colorless to light yellow liquid |
| Safety | 23-26-27-36/37/39-45 | Risk Codes | 34-22 |
| Molecular Structure |
|
Hazard Symbols |
 C
|
| Synonyms |
Dimethyl acetylenedicarboxylic acid;1,2-Bis(methoxycarbonyl)acetylene;Dimethyl ethynedicarboxylate;Di(carbomethoxy)acetylene;Dimethyl butynedioate;2-Butynedioic acid, dimethyl ester;Bis(methoxycarbonyl)acetylene;dimethyl but-2-ynedioate;Dimethyl but-2-yndioate;But-2-ynedioic acid dimethyl ester;Dimethyl 2-butynedioate;1, 2-Bis(methoxycarbonyl)acetylene;Methyl acetylenedicarboxylate;Acetylenedicarboxylic acid, dimethyl ester;1,2-Bis(methoxycarbonyl)ethyne;Acetylenedicarboxylic acid dimethyl ester;Acetylenedicarboxylic acid, dimethyl ester (8CI); |
Article Data | 40 |
Dimethyl acetylenedicarboxylate Synthetic route
| Conditions | Yield |
|---|---|
| With toluene-4-sulfonic acid In 1,2-dichloro-ethane; toluene Reflux; | 93% |
| With sulfuric acid at 20℃; for 24h; Inert atmosphere; | 88% |
| With sulfuric acid | |
| With toluene-4-sulfonic acid |
- 1114-20-1, 62675-22-3, 116631-94-8
trans-2,3-dibromobutenedioic acid dimethyl ester
- 762-42-5
dimethyl acetylenedicarboxylate
| Conditions | Yield |
|---|---|
| With zinc In tetrahydrofuran for 2h; Heating; | 93% |
| With zinc In tetrahydrofuran for 2h; Heating; Yield given; |
A
- 12083-48-6
bis(cyclopentadienyl)vanadium dichloride
B
- 762-42-5
dimethyl acetylenedicarboxylate
| Conditions | Yield |
|---|---|
| With chlorine In tetrachloromethane | A 68% B 37% |
| With Cl2 In tetrachloromethane | A 68% B 37% |
- 86625-25-4
3-methoxycarbonyl-5-pyrazolinone
- 762-42-5
dimethyl acetylenedicarboxylate
| Conditions | Yield |
|---|---|
| With [bis(acetoxy)iodo]benzene In methanol 1.) -23 deg C, 45 min; 2.) rt, 1 h; | 59% |
- 64995-84-2
dimethyl 2-oxo-3-triphenylphosphoranylidenebutanedioate
A
- 762-42-5
dimethyl acetylenedicarboxylate
B
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| at 500℃; under 0.01 Torr; | A 59% B n/a |
| at 500℃; under 0.001 - 0.1 Torr; for 1h; | A 59 % Spectr. B n/a |
- 68827-52-1
methyl 7-oxo-2-phenyl-7H-[1,2,4]triazolo[3,2-b][1,3]thiazine-5-carboxylate
- 67-56-1
methanol
A
- 762-42-5
dimethyl acetylenedicarboxylate
B
- 3414-94-6
3-phenyl-4,5-dihydro-1H-1,2,4-triazole-5-thione
| Conditions | Yield |
|---|---|
| Stage #1: methyl 7-oxo-2-phenyl-7H-[1,2,4]triazolo[3,2-b][1,3]thiazine-5-carboxylate With potassium hydroxide In methanol; water for 48h; Stage #2: methanol at 20℃; for 96h; | A n/a B 59% |
- 183586-23-4
(Z)-1-hydroperoxy-N-[(Z)-3-(methoxycarbonyl)-2-propenylidene]cyclohexylamine N-oxide
A
- 57314-32-6
Maleinaldehydsaeure-methylester
B
- 108-94-1
cyclohexanone
C
- 762-42-5
dimethyl acetylenedicarboxylate
D
- 183813-49-2
(Z)-4-[(E)-Hydroxyimino]-but-2-enoic acid methyl ester
| Conditions | Yield |
|---|---|
| In benzene for 0.5h; Heating; Further byproducts given; | A 32% B 6% C 32% D n/a |
- 183586-23-4
(Z)-1-hydroperoxy-N-[(Z)-3-(methoxycarbonyl)-2-propenylidene]cyclohexylamine N-oxide
A
- 108-94-1
cyclohexanone
B
- 762-42-5
dimethyl acetylenedicarboxylate
C
- 183586-28-9
(Z)-anti-methyl 4-(hydroxyimino)but-2-enoate
D
- 183813-49-2
(Z)-4-[(E)-Hydroxyimino]-but-2-enoic acid methyl ester
| Conditions | Yield |
|---|---|
| In benzene for 0.5h; Heating; Further byproducts given. Title compound not separated from byproducts; | A 6% B 32% C n/a D n/a |
- 58150-95-1
(1S,3aR)-1H-1,3a-Etheno-azulene-9,10-dicarboxylic acid dimethyl ester
A
- 58150-88-2
dimethyl heptalene-4,5-dicarboxylate
B
- 762-42-5
dimethyl acetylenedicarboxylate
C
- 275-51-4
azulene
| Conditions | Yield |
|---|---|
| In (2)H8-toluene at 60℃; under 750.06 Torr; for 30h; thermolyse, other pressure; |
- 116935-20-7
2-(2-thienyl)-4,5-dimethoxycarbonyl-1,3-dithiole
- 74-88-4
methyl iodide
A
- 2168-83-4
thiophene-2-carbodithioic acid methyl ester
B
- 762-42-5
dimethyl acetylenedicarboxylate
| Conditions | Yield |
|---|---|
| With n-butyllithium 1) 2 h -30 deg C THF hexane, 2) 2 h; Multistep reaction; |
Dimethyl acetylenedicarboxylate Chemical Properties
.jpg)
IUPAC Name: Dimethyl but-2-ynedioate
Molecular Formula: C6H6O4
Molecular Weight: 142.11 g/mol
Canonical SMILES: C(C(OC)=O)#CC(OC)=O
InChI: InChI=1/C6H6O4/c1-9-5(7)3-4-6(8)10-2/h1-2H3
EINECS: 212-098-4
Classification Code: Agricultural Chemical; Experimental pesticide; Unspecified / Unclassified pesticide
Product Categories: Aromatic Esters;Small molecule; Acetylenes; Acetylenic Carboxylic Acids & Their Derivatives
Sensitive: Light Sensitive
Surface Tension: 41.1 dyne/cm
Density: 1.205 g/cm3
Flash Point: 86.1 °C
Enthalpy of Vaporization: 44.05 kJ/mol
Boiling Point: 204.3 °C at 760 mmHg
Melting Point: -18 °C
Vapour Pressure of Dimethyl acetylenedicarboxylate (CAS NO.762-42-5): 0.265 mmHg at 25 °C
Dimethyl acetylenedicarboxylate Uses
Dimethyl acetylenedicarboxylate (CAS NO.762-42-5) is mainly used in organic synthesis. It is is a lachrymator and a vesicant.
Dimethyl acetylenedicarboxylate Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 550mg/kg (550mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: COMA | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(6), Pg. 55, 1984. |
| rat | LDLo | oral | 50mg/kg (50mg/kg) | National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 13, 1953. |
Dimethyl acetylenedicarboxylate Consensus Reports
Reported in EPA TSCA Inventory.
Dimethyl acetylenedicarboxylate Safety Profile
Poison by ingestion. A dienophile. Explosive reaction with 1-methylsilacyclopenta-2,4-diene at 150°C. Octakis(trifluorophosphine)dirhodium catalyzes explosive polymerization of the acid above 20°C. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: 
C
Risk Statements: 34-22
R34: Causes burns.
R22: Harmful if swallowed.
Safety Statements: 23-26-27-36/37/39-45
S23: Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27: Take off immediately all contaminated clothing.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
RTECS: ES0175000
F: 8-19
HazardClass: 8
PackingGroup of Dimethyl acetylenedicarboxylate (CAS NO.762-42-5): III
Dimethyl acetylenedicarboxylate Specification
Dimethyl acetylenedicarboxylate (CAS NO.762-42-5), its Synonyms are Acetylenedicarboxylic acid dimethyl ester ; 2-Butynedioic acid, 1,4-dimethyl ester ; 2-Butynedioic acid, dimethyl ester ; 1,2-Bis(methoxycarbonyl)acetylene ; Bis(methoxycarbonyl)acetylene . It is clear colorless to light yellow liquid.
What can I do for you?
Get Best Price
