Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Disodium 2-oxoglutarate dihydrate

Related Products

Hot Products

Name

Disodium 2-oxoglutarate dihydrate

EINECS 206-167-8
CAS No. 305-72-6 Density 1.499g/cm3
PSA 115.79000 LogP -3.29310
Solubility soluble Melting Point N/A
Formula C5H4Na2O5 Boiling Point 345.6 °C at 760 mmHg
Molecular Weight 190.063 Flash Point 177 °C
Transport Information N/A Appearance White powder.
Safety 22-24/25-45-36/37/39-26 Risk Codes 23/24/25-36/37/38
Molecular Structure Molecular Structure of 305-72-6 (Disodium 2-oxoglutarate dihydrate) Hazard Symbols T
Synonyms

Glutaricacid, 2-oxo-, disodium salt (8CI);Pentanedioic acid, 2-oxo-, disodium salt(9CI);2-Oxoglutaric acid disodium salt;Disodium 2-oxoglutarate;Disodium2-oxopentanedioate;Disodium a-ketoglutarate;a-Oxoglutaric acid disodium salt;Disodium 2-oxoglutarate;Pentanedioic acid, 2-oxo-, disodium salt;α-Ketoglutaric acid disodium salt;

Article Data 2

Disodium 2-oxoglutarate dihydrate Synthetic route

35818-60-1

2-oxoglutaric acid 1-ethyl ester

305-72-6

α-ketoglutaric acid disodium salt

Conditions
ConditionsYield
With [D]-sodium hydroxide; water-d2 for 0.00416667h; pH=11;>= 95 %Spectr.
328-50-7

α-ketoglutaric acid

305-72-6

α-ketoglutaric acid disodium salt

Conditions
ConditionsYield
With sodium hydroxide In water at 25 - 35℃; Reagent/catalyst; Large scale;
305-72-6

α-ketoglutaric acid disodium salt

2-oxo[3,3-2H]glutaric acid disodium salt

Conditions
ConditionsYield
With water-d2 at 80℃; for 3h; Substitution;100%
305-72-6

α-ketoglutaric acid disodium salt

71686-01-6

calcium alpha-ketaglutarate

Conditions
ConditionsYield
With calcium chloride In water at 65 - 70℃; Large scale;77%
3353-89-7

triphenylsulfonium bromide

305-72-6

α-ketoglutaric acid disodium salt

bis(triphenylsulfonium) 2-ketoglutaricacid

Conditions
ConditionsYield
In dichloromethane; water at 20℃;75%
In dichloromethane; water
305-72-6

α-ketoglutaric acid disodium salt

7646-85-7

zinc(II) chloride

293766-90-2

alpha-ketoglute zinc

Conditions
ConditionsYield
In water at 80 - 85℃; Large scale;73%
932-98-9

1-chloro-4-nitroso-benzene

305-72-6

α-ketoglutaric acid disodium salt

A

62558-67-2

4-(4'-hydroxy-phenylamino)-4-oxo-butanoic acid

B

123-30-8

4-amino-phenol

C

28443-50-7

2-amino-5-chlorophenol

D

81576-13-8

N-(4-chloro-2-hydroxyphenyl)succinamic acid

Conditions
ConditionsYield
With thiamine pyrophosphate; α-ketoglutarate dehydrogenase; magnesium chloride In water at 30℃; for 2h; 0.05M KH2PO4 buffer (pH 7.5); Further byproducts given. Yields of byproduct given;A n/a
B n/a
C n/a
D 2 mg
932-98-9

1-chloro-4-nitroso-benzene

305-72-6

α-ketoglutaric acid disodium salt

A

62558-67-2

4-(4'-hydroxy-phenylamino)-4-oxo-butanoic acid

B

28443-50-7

2-amino-5-chlorophenol

C

81576-12-7

N-(4-chlorophenyl)succinohydroxamic acid

D

81576-13-8

N-(4-chloro-2-hydroxyphenyl)succinamic acid

Conditions
ConditionsYield
With thiamine pyrophosphate; α-ketoglutarate dehydrogenase; magnesium chloride In water at 30℃; for 2h; 0.05M KH2PO4 buffer (pH 7.5); Further byproducts given. Yields of byproduct given;A n/a
B n/a
C 1.5 mg
D 2 mg
305-72-6

α-ketoglutaric acid disodium salt

2889-31-8

2-hydroxyglutaric acid

Conditions
ConditionsYield
With hydrogenchloride; sodium tetrahydroborate for 0.0833333h; Reduction;
305-72-6

α-ketoglutaric acid disodium salt

(S)-2-oxo[3-2H]glutaric acid disodium salt

Conditions
ConditionsYield
With isocitrate dehydrogenase; water-d2; NADPH at 37℃; for 2h; Substitution;

Disodium 2-oxoglutarate dihydrate Chemical Properties

Name:α-ketoglutaric acid,disodium salt(305-72-6)
Molecular Formula:C5H4O5.2Na
Molecular Weight: 190.06g/mol
EINECS: 206-167-8
Chemical Properties: white powder
Density: 1.499g/cm3
Boiling Point: 345.6°C at 760 mmHg
Flash Point: 177 °C
Solubility: soluble in water
Freely Rotating Bonds: 4   
Polarizability: 10-24cm3 
Enthalpy of Vaporization: 64.8 kJ/mol 
Vapour Pressure: 1.08E-05 mmHg at 25°C
    The chemical synonyms of α-ketoglutaric acid,disodium salt(305-72-6) are 2-oxo-pentanedioicacidisodiumsalt;DISODIUM 2-KETOGLUTARATE;DISODIUM 2-OXOGLUTARATE;ALPHA-KETOGLUTARIC ACID, SESQUISODIUM SALT;ALPHA-KETOGLUTARATE DISODIUM;ALPHA-KETOGLUTARIC ACID DISODIUM SALT;2-KETOGLUTARIC ACID DISODIUM SALT;2-KETOGLUTARIC ACID SODIUM SALT .The molecular structure of α-ketoglutaric acid,disodium salt(305-72-6) is.

Disodium 2-oxoglutarate dihydrate Uses

α-ketoglutaric acid,disodium salt(305-72-6) is used as pharmaceutical intermediate.

Disodium 2-oxoglutarate dihydrate Toxicity Data With Reference

1.    

orl-rat LD50:7.1 g/kg

    JAPTO*    Journal of Applied Toxicology 21 (2001),495.
2.    

orl-rat TDLo:2 g/kg

    JAPTO*    Journal of Applied Toxicology 21 (2001),495.
3.    

orl-rat TDLo:4 g/kg

    JAPTO*    Journal of Applied Toxicology 21 (2001),495.

Disodium 2-oxoglutarate dihydrate Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:  T
T:  Toxic
Risk Statements:  23/24/25-36/37/38
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed 
36/37/38:  Irritating to eyes, respiratory system and skin 
Safety Statements:  22-24/25-45-36/37/39-26
22:  Do not breathe dust 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
24/25:  Avoid contact with skin and eyes 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 305-72-6