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Name	Domperidone maleate	EINECS	801-827-7
CAS No.	99497-03-7	Density	N/A
PSA	153.42000	LogP	3.00290
Solubility	N/A	Melting Point	236 - 239 °C
Formula	C₂₂H₂₄ClN₅O₂^.C₄H₄O₄	Boiling Point	778.5 °C at 760 mmHg
Molecular Weight	541.98	Flash Point	424.7 °C
Transport Information	N/A	Appearance	N/A
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;R 33,812;but-2-enedioic acid; 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;KW-5338;

Domperidone maleate Chemical Properties

IUPAC Name:5-Chloro-1-[1-[3-(2-oxo-1,3-dihydrobenzoimidazol-1-yl)propyl]-4-piperidyl]-1,3-dihydrobenzoimidazol-2-one maleate
Molecular Formula:C₂₂H₂₄ClN₅O₂^.C₄H₄O₄
Molecular Weight:541.99 g/mol
Melting Point:236 - 239 °C
Appearance: white powder

Domperidone maleate Uses

Domperidone maleate (CAS NO.99497-03-7) is a dopamine antagonist used as an antiemetic for the short term treatment of nausea and vomiting of various etiologies.

Domperidone maleate Toxicity Data With Reference

Toxicity: ORL-RAT LD50 5243 mg kg^-1, IPR-RAT LD50 61 mg kg^-1, ORL-MUS LD50 > 8000 mg kg^-1 .

Domperidone maleate Analytical Methods

Domperidone maleate(99497-03-7) was determined by several methods including colorimetric methods, spectrophotometric methods, high-performance thin-layer chromatography, high-performance liquid chromatography and titrimetric methods.

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