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Domperidone maleate

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Domperidone maleate

EINECS 801-827-7
CAS No. 99497-03-7 Density N/A
PSA 153.42000 LogP 3.00290
Solubility N/A Melting Point 236 - 239 °C
Formula C22H24ClN5O2.C4H4O4 Boiling Point 778.5 °C at 760 mmHg
Molecular Weight 541.98 Flash Point 424.7 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 99497-03-7 (Domperidone maleate) Hazard Symbols N/A

5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;R 33,812;but-2-enedioic acid; 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;KW-5338;


Domperidone maleate Chemical Properties

IUPAC Name:5-Chloro-1-[1-[3-(2-oxo-1,3-dihydrobenzoimidazol-1-yl)propyl]-4-piperidyl]-1,3-dihydrobenzoimidazol-2-one maleate
Molecular Formula:C22H24ClN5O2.C4H4O4
Molecular Weight:541.99 g/mol
Melting Point:236 - 239 °C
Appearance: white powder

Domperidone maleate Uses

Domperidone maleate (CAS NO.99497-03-7) is a dopamine antagonist used as an antiemetic for the short term treatment of nausea and vomiting of various etiologies.

Domperidone maleate Toxicity Data With Reference

Toxicity: ORL-RAT LD50 5243 mg kg-1, IPR-RAT LD50 61 mg kg-1, ORL-MUS LD50 > 8000 mg kg-1 .

Domperidone maleate Analytical Methods

Domperidone maleate(99497-03-7) was determined by several methods including colorimetric methods, spectrophotometric methods, high-performance thin-layer chromatography, high-performance liquid chromatography and titrimetric methods.

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