- Enrofloxacin
- Enrofloxacin hydrochloride
- 93-10-72-Quinolinecarboxylicacid
- 93107-08-53-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1)
- 93107-30-33-Quinolinecarboxylicacid, 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-
- 931101-84-7Plasminogen (synthetichuman variant V10153)
- 931-10-2Cyclohexanamine,2-methyl-, (1R,2R)-rel-
- 931105-37-23-Pyridinecarboxylicacid, 5-bromo-2-fluoro-, methyl ester
- 93111-25-2Benzoic-2,3,5,6-d4acid, 4-fluoro-
- 93111-26-3Benzene-2,3,5,6-d4-methanol,4-fluoro- (9CI)
- 931114-31-7(3-amino-1H-pyrazol-4-yl)(phenyl)methanone
- 931114-35-1Methanone, (5-amino-1H-pyrazol-4-yl)-2-pyridinyl-
Hot Products
- 2216-51-5Cyclohexanol,5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
- 128-08-5N-Bromosuccinimide
- 87-51-41H-Indole-3-acetic acid
- 58-93-5Hydrochlorothiazide
- 64485-93-4Cefotaxime sodium
- 54060-30-93-Aminophenylacetylene
- 54965-24-1Tamoxifen citrate
- 90776-59-3β-Methyl vinyl phosphate
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Enrofloxacin |
EINECS | 618-911-2 |
| CAS No. | 93106-60-6 | Density | 1.385 g/cm3 |
| PSA | 65.78000 | LogP | 2.31850 |
| Solubility | Soluble in chloroform. Slightly soluble in water. Also soluble in dilute KOH | Melting Point |
225 °C |
| Formula | C19H22FN3O3 | Boiling Point | 560.5 °C at 760 mmHg |
| Molecular Weight | 359.4 | Flash Point | 292.8 °C |
| Transport Information | N/A | Appearance | Pale yellow crystals |
| Safety | 26-36/37 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
1-Cyclopropyl-6-fluoro-7-(4-ethyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid;Alsir;BAY-Vp 2674;Baytril;Biofloxavet;CFPQ;Enrocin;Enrofan;Enrogil;Enroxil;N-Ethylciprofloxacin;N'-Ethylciprofloxacin;3-Quinolinecarboxylicacid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-; |
Article Data | 17 |
Enrofloxacin Synthetic route
- 5308-25-8
4-ethylpiperazine
- 86393-33-1
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| With nano iron oxide on ZrO2 coated sulfonic acid In water for 0.316667h; Solvent; Temperature; Reagent/catalyst; Reflux; | 97% |
| at 150℃; for 0.416667h; Microwave irradiation; | 93% |
| With aluminum tri-bromide In ethanol at 75℃; for 4h; Reagent/catalyst; Solvent; Temperature; | 92% |
- 5308-25-8
4-ethylpiperazine
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| With aluminum (III) chloride In i-Amyl alcohol at 140℃; for 8h; Temperature; | 91.8% |
- 131776-44-8
ditrimethylsilyl N-cyclopropyl-3-(4-ethyl-1-piperazinyl)anilinomethylenemalonate
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| 90% |
- 5308-25-8
4-ethylpiperazine
- 86393-33-1
7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
B
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| In water for 13h; Heating; | A n/a B 89% |
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; potassium iodide In water; acetonitrile at 20℃; for 12h; | 70% |
- 5308-25-8
4-ethylpiperazine
- 98349-24-7
ethyl 2,4,5-trifluorobenzoylacetate
- 4637-24-5
N,N-dimethyl-formamide dimethyl acetal
- 765-30-0
Cyclopropylamine
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| Yield given. Multistep reaction; |
- 86483-51-4
ethyl 2,4-dichloro-5-fluoro-benzoyl-acetate
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1: acetic anhydride / 2 h / Heating 2: 92 percent / ethanol / 1 h / Ambient temperature 3: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 4: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 5: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
- 86483-53-6
3-Cyclopropylamino-2-(2,4-dichlor-5-fluorbenzoyl)acrylsaeure-ethylester
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 2: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 3: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
- 86483-54-7
ethyl 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylate
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 2: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme |
- 86393-34-2
2,4-dichloro-5-fluorobenzoyl chloride
- 93106-60-6
enrofloxacin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 62 percent / pyridine / dioxane / 1.) 2 h, room temperature, 2.) 1 h, 70 - 80 deg C. 2: 85 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 3: 92 percent / conc. H2SO4 / H2O; acetic acid / 1.5 h / Heating 4: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme | |
| Multi-step reaction with 7 steps 1: Mg/ethanol, CCl4 / ethanol; toluene / 1.) 0 to -5 deg C, 2.) 12 h, room temperature 2: p-toluenesulfonic acid / H2O / 5 h / Heating 3: acetic anhydride / 2 h / Heating 4: 92 percent / ethanol / 1 h / Ambient temperature 5: 90 percent / potassium carbonate / dimethylformamide / 2 h / 140 - 150 °C 6: 93 percent / conc. H2SO4 / H2O / 1.5 h / Heating 7: 86 percent / dimethylsulfoxide / 2.5 h / 140 °C View Scheme | |
| Multi-step reaction with 2 steps 1.1: tributyl-amine / 1 h / 70 °C 1.2: 15 °C / 1520.1 Torr 2.1: cesium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene / 125 - 130 °C 2.2: 8 h / 85 °C View Scheme |
Enrofloxacin Chemical Properties
.jpg)
IUPAC Name: 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
Molecular Weight: 359.394683 [g/mol]
Molecular Formula: C19H22FN3O3
XLogP3: -0.2
H-Bond Donor: 1
H-Bond Acceptor: 7
Index of Refraction: 1.634
Molar Refractivity: 92.8 cm3
Molar Volume: 259.3 cm3
Surface Tension: 62 dyne/cm
Density: 1.385 g/cm3
Flash Point: 292.8 °C
Enthalpy of Vaporization: 88.7 kJ/mol
Boiling Point: 560.5 °C at 760 mmHg
Vapour Pressure: 2.13E-13 mmHg at 25 °C
Water Solubility: 3400 mg/L at 25 °C
Appearance: Pale Yellow Crystals
Melting Point: 225 °C
Classification Code of Enrofloxacin (CAS NO.93106-60-6): Antibacterial [veterinary]; Antineoplastic agents; Drug / Therapeutic Agent; Mutation data
Product Categories: Antibiotics for Research and Experimental Use; Biochemistry; Quinolones (Antibiotics for Research and Experimental Use); Intermediates & Fine Chemicals; Pharmaceuticals; Veterinaries
Enrofloxacin Uses
Enrofloxacin (CAS NO.93106-60-6) is widely used in the treatment of human disease. It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration dependent, with susceptible bacteria cell death occurring within 20-30 minutes of exposure. Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and is active in both stationary and growth phases of bacterial replication.
Enrofloxacin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 200mg/kg (200mg/kg) | VMR, Veterinary Medical Review. Vol. 2, Pg. 87, 1987. | |
| mouse | LD50 | oral | 4336mg/kg (4336mg/kg) | VMR, Veterinary Medical Review. Vol. 2, Pg. 87, 1987. | |
| rabbit | LD50 | oral | 500mg/kg (500mg/kg) | VMR, Veterinary Medical Review. Vol. 2, Pg. 87, 1987. | |
| rat | LD50 | oral | 5gm/kg (5000mg/kg) | VMR, Veterinary Medical Review. Vol. 2, Pg. 87, 1987. |
Enrofloxacin Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS of Enrofloxacin (CAS NO.93106-60-6): VB1993650
Enrofloxacin Specification
Enrofloxacin (CAS NO.93106-60-6), its Synonyms are 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid ; 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ; BAY VP 2674 ; Enrofloxacine ; Enrofloxacino ; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo- ; 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- .
What can I do for you?
Get Best Price
