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Fenspiride hydrochloride

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Name

Fenspiride hydrochloride

EINECS N/A
CAS No. 5053-08-7 Density 1.19g/cm3
PSA 41.57000 LogP 2.87220
Solubility N/A Melting Point 235-238oC (dec.)
Formula C15H20 N2 O2 . Cl H Boiling Point 474.3°Cat760mmHg
Molecular Weight 296.797 Flash Point 240.6°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intraperitoneal, and intravenous routes. A bronchodilator and antiadrenergic agent. When heated to decomposition it emits very toxic fumes of NOx and HCl. Risk Codes 20/21/22
Molecular Structure Molecular Structure of 5053-08-7 (Fenspiride hydrochloride) Hazard Symbols Xn
Synonyms

1-Oxa-3,8-diazaspiro[4.5]decan-2-one,8-(2-phenylethyl)-, monohydrochloride (9CI);1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-phenethyl-, monohydrochloride (8CI);8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride; Decaspir;Decaspiride; Erespal; Fenspiride hydrochloride; Fluiden; JP 428; NAT 333; NDR5998A; Pneumorel; Tegencia; Viarespan

 

Fenspiride hydrochloride Chemical Properties

DECASPIRIDE HYDROCHLORIDE(5053-08-7) appears the white power.
And DECASPIRIDE HYDROCHLORIDE(5053-08-7) has some properties listed in the following.
Molecular Formula:C15H20N2O2 .ClH
Molecular Weight:296.83
Density:1.19g/cm3
Boiling Point:474.3°C at760mmHg
Flash Point:240.6°C
Properties: A solid. Mp: 232–233°C (decomp).

Fenspiride hydrochloride Toxicity Data With Reference

1.   

orl-rat LD50:437 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1263.
2.   

ivn-rat LD50:122 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 193 (1971),111.
3.   

orl-mus LD50:250 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 193 (1971),111.
4.   

ipr-mus LD50:230 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 19 (1969),1263.
5.   

ivn-mus LD50:106 mg/kg

   MEIEDD    Merck Index. 10 (1983),575.
6.   

ivn-dog LD50:74 mg/kg

   BCFAAI    Bollettino Chimico Farmaceutico. 117 (1978),343.
7.   

orl-gpg LD50:260 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 193 (1971),111.
8.   

ipr-gpg LD50:210 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 193 (1971),111.

Fenspiride hydrochloride Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. A bronchodilator and antiadrenergic agent.
When heated to decomposition DECASPIRIDE HYDROCHLORIDE(5053-08-7)  emits very toxic fumes of NOx and HCl.
Hazard Codes : Xn 
 Risk Statements : 20/21/22 
 Safety Statements : 36 
 WGK Germany : 3
 RTECS : RO0375000
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