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Fmoc-L-4-Thiazolylalanine

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Name

Fmoc-L-4-Thiazolylalanine

EINECS N/A
CAS No. 205528-32-1 Density 1.379 g/cm3
PSA 116.76000 LogP 4.06840
Solubility N/A Melting Point 178.2 °C
Formula C21H18N2O4S Boiling Point 647.5 °C at 760 mmHg
Molecular Weight 394.451 Flash Point 345.4 °C
Transport Information N/A Appearance white powder
Safety 24/25 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 205528-32-1 (FMOC-L-4-THIAZOLYLALANINE) Hazard Symbols IrritantXi
Synonyms

4-Thiazolepropanoicacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,(S)-;

 

Fmoc-L-4-Thiazolylalanine Chemical Properties

Molecular Formula: C21H18N2O4S
Molar mass: 394.44 g/mol
Density: 1.378 g/cm3
Flash Point: 345.4 °C
Index of Refraction: 1.654
Boiling Point: 647.5 °C at 760 mmHg
Vapour Pressure: 1.19E-17 mmHg at 25°C
Melting point: 178.2 °C
Storage temp: Store at -15°C
Appearance: White powder
Product categories: Phenylalanine analogs and other aromatic alpha amino acids
Structure of Fmoc-L-4-Thiazolylalanine (205528-32-1):

XLogP3-AA: 3.7
H-Bond Donor: 2
H-Bond Acceptor: 5
IUPAC Name: (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(1,
3-thiazol-4-yl)propanoic acid
Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CSC=N4)C(=O)O
Isomeric SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CSC=N4)C(=O)O
InChI: InChI=1S/C21H18N2O4S/c24-20(25)19(9-13-11-28-12-22-13)23-21(26)27-10-18-
16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,11-12,18-19H,9-10H2,(H,23,
26)(H,24,25)/t19-/m0/s1 
InChIKey: LSBAZFASKHLHKB-IBGZPJMESA-N

Fmoc-L-4-Thiazolylalanine Toxicity Data With Reference

Carcinogenicity of Fmoc-L-4-Thiazolylalanine (205528-32-1) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. And its toxicological properties have not been fully investigated.

Fmoc-L-4-Thiazolylalanine Safety Profile

Hazard Codes: Xi
Risk Statements:
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements:
24:  Avoid contact with skin
25:  Avoid contact with eyes

Fmoc-L-4-Thiazolylalanine Specification

 Fmoc-L-4-Thiazolylalanine (205528-32-1) also can be called 3-Thiazol-4-yl-L-alanine, N-FMOC protected ; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1,3-thiazol-4-yl)propanoic Acid .It is hazardous,so the first aid measures and others should be known.Such as: When on the skin: first,should  flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing. Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.Notes to physician: Treat supportively and symptomatically.
In addition, Fmoc-L-4-Thiazolylalanine (205528-32-1) is not compatible with strong oxidizing agents, and you must not take it with incompatible materials.And also prevent it to broken down into hazardous decomposition products: nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.

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