Synthesis and evaluation of novel E-2-(2-thienyl)- and Z-2-(3-thienyl)-3- arylacrylonitriles as antifungal and anticancer agents

DOI: 10.1002/ardp.200700082

Source and publish data:

Archiv der Pharmazie p. 603 - 606 (2007)

Update date:2022-08-05

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Authors:

Quiroga, Jairo

Cobo, Debora

Insuasty, Braulio

Abonia, Rodrigo

Nogueras, Manuel

Cobo, Justo

Vasquez, Yelkaira

Gupta, Mahabir

Derita, Marcos

Zacchino, Susana

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Article abstract of DOI:10.1002/ardp.200700082

A series of 3-aryl-2-(2-thienyl)acrylonitriles 7 and 3-aryl-2-(3-thienyl) acrylonitriles 8 were synthesized by the reaction of aromatic aldehydes 6 with 2- and 3-thienylacetonitriles 4 and 5, and evaluated for antifungal and cytotoxic activities against a

Full text of DOI:10.1002/ardp.200700082

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