Synthesis and structure-affinity relationships of selective high-affinity 5-HT4 receptor antagonists: Application to the design of new potential single photon emission computed tomography tracers

DOI: 10.1021/jm300943r

Source and publish data:

Journal of Medicinal Chemistry p. 9693 - 9707 (2012)

Update date:2022-09-26

Topics:

Authors:

Dubost, Emmanuelle

Dumas, Noé

Fossey, Christine

Magnelli, Rosa

Butt-Gueulle, Sabrina

Ballandonne, Céline

Caignard, Daniel H.

Dulin, Fabienne

Sopkova De-Oliveira Santos, Jana

Millet, Philippe

Charnay, Yves

Rault, Sylvain

Cailly, Thomas

Fabis, Frederic

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm300943r

The work described herein aims at finding new potential ligands for the brain imaging of 5-HT₄ receptors (5-HT₄Rs) using single-photon emission computed tomography (SPECT). Starting from the nonsubstituted phenanthridine compound 4a,

Full text of DOI:10.1021/jm300943r

Products guided by the article

Product name:2-fluoro-3-(trimethylsilanyl)phenylboronic Acid

Cas No:1410703-15-9

R&D Labs maybe for 1410703-15-9

Kunming Biohome Technology Co. Ltd.

website:http://www.biohometech.com/

Contact:86-871-67428869

Address:kunming
shanghai hekang chemical co.ltd

Contact:021-54173790

Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)

Contact:86-532-67773200; 15689126900

Address:Qidu town,Linzi district,Zibo city,Shandong province,China
Xi'an North Information Industry Co., Ltd. Weilv Chemical Department

Contact:+86-29-88156413

Address:Jixiang Road 99 Xi'an Shaanxi Province
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang

Relevant to this article

A general organocatalytic approach toward the enantioselective total synthesis of indolizidine based alkaloids

Doi:10.1021/ol302871u
(2012)
Bromenium-catalysed tandem ring opening/cyclisation of vinylcyclopropanes and vinylcyclobutanes: A metal-free [3+2+1]/[4+2+1] cascade for the synthesis of chiral amidines and computational investigation

Doi:10.1002/chem.201103556
(2012)
A new disubstituted polyacetylene bearing DDTC moieties: Postfunctional synthetic strategy, selective and sensitive chemosensor towards mercury ions

Doi:10.1016/j.polymer.2012.10.006
(2012)
Large scale synthesis of 2′-Amino-LNA thymine and 5-methylcytosine nucleosides

Doi:10.1021/jo302036h
(2012)
A versatile method for the synthesis of γ-pyrones

Doi:10.1139/v2012-067
(2012)
A ready synthesis of intermediates containing the A-ring substructure of taxol: A Diels-Alder route to the B-seco taxane series

Doi:10.1021/jo00040a064
(1992)

Article Doi