Synthesis of 20-Deethylsilicine from a Second-Generation 2-Cyano-Δ3-piperidine Synthon

DOI: 10.1021/jo00050a012

Source and publish data:

Journal of Organic Chemistry p. 6414 - 6421 (1992)

Update date:2022-08-05

Topics: Synthesis Synthon

Authors:

Grierson, David S.

Bettiol, Jean-Luc

Buck, Ildiko

Husson, Henri-Philippe

Rubiralta, Mario

Diez, Anna

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Article abstract of DOI:10.1021/jo00050a012

The Zn(2+) ion mediated reaction of the 2-cyano-Δ³-piperidine 9a (X = SO2C6H5) with the silyl enol ether of Na-methyl-2-acetylindole (24) led to the formation of compounds 29a,b (70percent) resulting from introduction of the acetylindole moiety

Full text of DOI:10.1021/jo00050a012

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