A selective reaction that can be used to attach moenomycin to solid supports and proteins

DOI: 10.1016/0040-4039(96)01035-0

Source and publish data:

Tetrahedron Letters p. 5087 - 5090 (1996)

Update date:2022-08-02

Topics:

Authors:

Kempin, Uwe

Hennig, Lothar

Mueller, Dietrich

Markus, Astrid

Welzel, Peter

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Article abstract of DOI:10.1016/0040-4039(96)01035-0

A selective reaction at unit A of the antibiotic moenomycin A (1) has been developed: Reaction of 1 with o-nitrobenzenediazonium chloride cleanly yielded 12. This compound is as active as moenomycin against Staph. aureus SG 511 and as an in-vitro transglycosylase inbibitor.

Full text of DOI:10.1016/0040-4039(96)01035-0

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