Synthesis of bromoxone

DOI: 10.1016/S0040-4039(00)78490-5

Source and publish data:

Tetrahedron Letters p. 8759 - 8760 (1994)

Update date:2022-07-29

Topics:

Authors:

Gautier, Elisabeth C. L.

Lewis, Norman J.

McKillop, Alexander

Taylor, Richard J. K.

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Article abstract of DOI:10.1016/S0040-4039(00)78490-5

A short synthetic route to the natural product bromoxone is reported (5 steps, 15% overall yield), involving regioselective monoepoxidation of an electrolytically-derived quinone monoketal followed by stereoselective ketone reduction.

Full text of DOI:10.1016/S0040-4039(00)78490-5

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