Bioorganic and Medicinal Chemistry Letters p. 2043 - 2048 (1999)
Update date:2022-08-03
Topics:
Briganti, Fabrizio
Scozzafava, Andrea
Supuran, Claudiu T.
Sulfonylamido(ureido) derivatives of histamine were synthesized by an original procedure in order to obtain tight-binding activators of the zinc enzyme carbonic anhydrase (CA), exploiting the binding energy of the alkyl/arylsulfonyl moieties with amino acid residues at the entrance of the active site. In contrast to the lead molecule, histamine, the new derivatives possessed higher affinity for three different CA isozymes, as evidenced by compairing the affinity constants of these compounds for isozyme CA II.
View MoreShifang Taifeng New Flame Retardant Co., Ltd
Contact:02884721008
Address:tingjiang industrial park, hefeng town
Shanghai Rainbow Chemistry Co., Ltd.
Contact:+86-21-64968086-5815/5812
Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.
Contact:+86-21-64891143
Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Contact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Contact:+86-25-85281586
Address:13F,Bld2#,South of Longpan Road
Doi:10.1016/j.tet.2004.09.066
(2004)Doi:10.1016/j.bmcl.2003.08.050
(2003)Doi:10.1016/j.tetlet.2016.02.043
(2016)Doi:10.1016/S0040-4039(00)01709-3
(2000)Doi:10.1021/jo00972a012
(1972)Doi:10.1016/S0957-4166(00)00282-2
(2000)
