Studies on the alkylation of β-oxo thioamides with α-bromoketones: Selective cyclization of the intermediate α-oxo ketene-N,S-acetals to thiophene derivatives

Article abstract of DOI:10.1080/10426509708031604

The addition of enolate anions obtained from substituted aryl methyl ketones in the presence of NaH and DMF to phenyl isothiocyanate on subsequent alkylation with phenacyl bromide or α-bromo propiophenone underwent intramolecular cyclization involving the

Full text of DOI:10.1080/10426509708031604

This article was downloaded by: [University of Auckland Library]
On: 11 December 2014, At: 23:50
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office:
Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK
Phosphorus, Sulfur, and Silicon and the
Related Elements
Publication details, including instructions for authors and subscription
information:
http://www.tandfonline.com/loi/gpss20
STUDIES ON THE ALKYLATION OF β-OXO
THIOAMIDES WITH α-BROMOKETONES:
SELECTIVE CYCLIZATION OF THE
INTERMEDIATE α-OXO KETENE-N, S-
ACETALS TO THIOPHENE DERIVATIVES
S. Suma a , N. K. Ushakumari a & C. V. Asokan a
a School of Chemical Sciences, Mahatma Gandhi University ,
Priyadarshini Hills, Kottayam, 686 560, Kerala, India
Published online: 24 Sep 2006.
To cite this article: S. Suma , N. K. Ushakumari & C. V. Asokan (1997) STUDIES ON THE ALKYLATION OF β-
OXO THIOAMIDES WITH α-BROMOKETONES: SELECTIVE CYCLIZATION OF THE INTERMEDIATE α-OXO KETENE-
N, S-ACETALS TO THIOPHENE DERIVATIVES, Phosphorus, Sulfur, and Silicon and the Related Elements,
131:1, 161-171, DOI: 10.1080/10426509708031604
To link to this article: http://dx.doi.org/10.1080/10426509708031604
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the information (the
“Content”) contained in the publications on our platform. However, Taylor & Francis, our
agents, and our licensors make no representations or warranties whatsoever as to the
accuracy, completeness, or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and are not the views
of or endorsed by Taylor & Francis. The accuracy of the Content should not be relied upon
and should be independently verified with primary sources of information. Taylor and Francis
shall not be liable for any losses, actions, claims, proceedings, demands, costs, expenses,
damages, and other liabilities whatsoever or howsoever caused arising directly or indirectly in
connection with, in relation to or arising out of the use of the Content.
This article may be used for research, teaching, and private study purposes. Any substantial
or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or
distribution in any form to anyone is expressly forbidden. Terms & Conditions of access and
use can be found at http://www.tandfonline.com/page/terms-and-conditions