Chemistry Letters p. 651 - 654 (1980)
Update date:2022-08-03
Topics:
Hayashi, Sei-ichi
Nakai, Takeshi
Ishikawa, Nobuo
Defluorinative hydrolysis (or alcoholysis) of gem-difluoroolefins (1) easily prepared via the facile difluoromethylenation of carbonyl compounds afforded the carboxylic acids (or esters).The homologation method was applied to the synthesis of anti-inflammatory ibuprofen.Furthermore, defluorinative hydrolysis of monofluoroolefins obtained via the reduction of 1 gave the aldehydes.
View MoreFujian Wanke Pharmaceutical Co., LTD.
Contact:+86-598-5026002
Address:Economic development zone,jiangle county
Shanghai better-in Medical Technology Co.,LTD.
Contact:+86-21-38921049
Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)
Contact:86 512 57910558
Address:qianjin M road
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Antaeus Bio-technology Co., LTD(expird)
Contact:021-31252569
Address:shanghai pudong
Doi:10.1021/ja01157a108
(1950)Doi:10.1016/j.tet.2004.06.031
(2004)Doi:10.1021/jo00315a031
(1981)Doi:10.1055/s-2005-865219
(2005)Doi:10.1002/ejoc.201901060
(2020)Doi:10.1021/ja047488e
(2004)
