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ChemComm
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COMMUNICATION
Journal Name
is commonly employed in a majority of thiol probes,6-10 the low
cytotoxicity of BODIPY-TS provides another advantage for biological
thiol sensing.
and S. H. Snyder, Nat. Cell Biol., 2001, D3,O1I:9130..1039/C5CC05390K
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21 B. Zhang, D. Duan, C. Ge, J. Yao, Y. Liu, X. Li and J. Fang, J.
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In summary, the thiosulfonate scaffold was employed to
create a turn-on thiol probe BODIPY-TS for the first time. The
probe has low toxicity, and features high selectivity, low
detection limit, fast response and quantitative reaction to
thiols. The structural novelty of BODIPY-TS would guide the
development of novel thiol sensors and protein thiol labeling
agents.
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27 V. F. Pais, P. Remon, D. Collado, J. Andreasson, E. Perez-
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ACKNOWLEDGEMENTS
The financial supports from the Lanzhou University (lzujbky-
2014-56) and Natural Science Foundation of Gansu Province
(145RJZA225) are greatly acknowledged.
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TOC
Thiosulfonate scaffold was applied to design selective and
turn-on thiol probes for the first time.
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4 | J. Name., 2012, 00, 1-3
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