SYNTHESIS AND MOLECULAR STRUCTURE OF PROLAME, N-(3-HYDROXY-1,3,5(10)-ESTRATRIEN-17β-YL)-3-HYDROXYPROPYLAMINE; AN AMINO-ESTROGEN WITH PROLONGED ANTICOAGULANT AND BRIEF ESTROGENIC EFFECTS

DOI: 10.1016/0039-128X(85)90044-3

Source and publish data:

Steroids p. 151 - 158 (1985)

Update date:2022-08-03

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Authors:

Fernandez-G., Juan M.

Rubio-Arroyo, Manuel F.

Soriano-Garcia, Manuel

Toscano, R. A.

Perez-Cesar, M. del Carmen

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Article abstract of DOI:10.1016/0039-128X(85)90044-3

The synthesis and molecular structure of prolame, N-(3-hydroxy-1,3,5(10)-estratrien-17β-yl)-3-hydroxypropylamine, is described.It was characterized by ir, nmr, mass spectrometry and chemical analysis.The crystal structure of this compound was determined by single-crystal x-ray diffraction.Prolame belongs to space group P2₁2₁2₁.Cell dimensions are: a = 8.356(2), b = 13.343(4) and c = 16.119(4) Angstroem.Z = 4; R = 4.1percent.

Full text of DOI:10.1016/0039-128X(85)90044-3

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