ChemComm
Communication
M. J. Smith is acknowledged for chromatography support.
Financial support from NRSC-Catalysis grant 200910018B is
gratefully acknowledged.
Notes and references
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Scheme 3 Effect of double bond geometry on ee and regioselectivity.
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Scheme 4 Cross metathesis between 1,4-diene 2d and ethyl acrylate 4.
pleased to find that the reaction also proceeded successfully
with (Z,E)-1g affording similar regio- and enantioselectivity to
that with (E,E)-1f, while no double bond isomerization was
detected in 2g. These remarkable results show that the geometry
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effect on both the regio- and enantioselectivity (Scheme 3). An
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via cross metathesis16 (Scheme 4) for future synthetic applica-
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c
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Chem. Commun., 2013, 49, 3309--3311 3311