Journal of Organic Chemistry p. 705 - 708 (1993)
Update date:2022-08-16
Topics:
Patrick, Timothy B.
Khazaeli, Sadegh
Nadji, Sourena
Hering-Smith, Katy
Reif, Dirk
The reaction of xenon difluoride with primary carboxylic acids involves a free-radical mechanism.Trifluoroacetic acid (1) decarboxylates in benzene to give (trifluoromethyl)benzene (2). 6-Hexenoic acid (3) produces a free radical in a radical clock reaction in which the kabs (25 deg C) for XeF2 was determined as 1.1 * 106 M-1 s-1.The primary radical from hexanoic acid was spin-trapped to give ESR signals diagnostic for the alkyl radical.Secondary acids were shown to proceed through a trivalent intermediate, but its exact nature was not proven.The acid 6 gave a rearranged product (7) characteristic of carbocations, whereas the diacid 8 gave difluoro compounds without stereoselectivity.The tertiary bicyclic acids 13 and 15 gave products only from solvent hydrogen abstraction strongly indicative of free radicals.
View MoreZhejiang Sucon Silicone Co.,Ltd
Contact:+86-575-88046692
Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Xinxiang Junlong Biological Technology Co., Ltd.
website:https://junlongbio.lookchem.com/
Contact:86-13525059581
Address:Xinxiang City, Henan Province
Tangshan Wisdom Trading Co.,Ltd
Contact:86 315 2222979
Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
Contact:+86-519-86339586,13584329896
Address:Changzhou Scientific and Education Park
FREEBARQUE DEVELOPMENT GROUP LIMITED
Contact:+86(0)10-5109 5335 or 5109 5345
Address:Room602,Block1-B,LINGDI OFFICE,NO.13 BEIYUAN ROAD
Doi:10.1002/kin.550261103
(1994)Doi:10.1016/S0957-4166(00)80218-9
(1993)Doi:10.1021/acs.macromol.1c00246
(2021)Doi:10.1016/j.mcat.2021.111671
(2021)Doi:10.1016/j.jallcom.2020.155567
(2020)Doi:10.1246/cl.2006.834
(2006)