F. Nicks, R. Aznar, D. Sainz, G. Muller, A. Demonceau
FULL PAPER
Microwave Heating: A 10-mL glass vial containing a Teflon®-
coated stir bar was charged with the catalyst (0.004 mmol) and 4-
acetoxybenzoic acid (0.5 mmol, 90 mg) and then purged of air
(three vacuum–nitrogen cycles) before a stock solution (2.6 mL)
containing 1-hexyne (0.75 mmol) and dodecane (internal standard)
in toluene was added. The vial was capped under nitrogen, heated
to 160 °C (monitored by IR sensor), and then held at that tempera-
ture in a CEM Discover instrument with 150-W microwave power.
No ramp and no simultaneous cooling were applied. After rapid
air-cooling by the unit, the reaction mixture was analyzed by GC.
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Supporting Information (see also the footnote on the first page of
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Acknowledgments
The Belgian team thanks the Fonds pour la Formation à la Recher-
che dans l’Industrie et dans l’Agriculture (FRIA) for a fellowship
to F. N. and the Fonds National de la Recherche Scientifique
(FNRS), Brussels for financial support of this work (grants FRFC
2.4565.07 and 2.4645.07) and for the purchase of major instrumen-
tation. The Barcelona team thanks the Spanish Ministerio de Edu-
cación y Ciencia (MEC) (project CTQ2007-61058/BQU). R. A.
thanks the Departament d’Universitats, Recerca i Societat de la
Informació de la Generalitat de Catalunya (DURSI) for the award
of a Ph.D. grant.
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