Bis(ethylsulfonamide)amines via nucleophilic ring-opening ofchiral aziridines. Application to Ti-mediated addition of diethylzinc to benzaldehyde

Article abstract of DOI:10.1016/S0957-4166(97)00410-2

Homochiral bis(N-trifiyl-2-alkyl-2-aminoethyl)amines, obtained from N- trifiyl-2-alkylaziridines via reaction with benzylamine, catalyze the titanium-mediated addition of diethylzinc to benzaidehyde to yield 1 - phenylpropanol in up to 78% ee in the prese