258
R. SINGH ET AL.
(2-Hydroxymethyl-pyrrolidin-1-yl)-(7-methoxy-2,2-dimethyl-2H-
chromen-4-yl)-methanone (18a)
1
IR (neat): 2918, 1612, 1442, 1145, 756 cmꢁ1; H NMR (300 MHz, CDCl3): d
6.93 (dd, 1H, J ¼ 2, 8.1), 6.42 (dd, 1H, J ¼ 2, 8.1), 6.40 (s, 1H), 5.56 (s, 1H), 4.99
(bs, 1H), 4.32–4.29 (m, 1H), 3.77 (s, 3H), 3.71–3.67 (m, 1H), 3.46–3.40 (m, 1H),
3.29–3.26 (m, 1H), 2.12–2.08 (m, 1H), 1.83–1.61 (m, 3H), 1.44 (s, 3H), 1.42 (s,
3H); 13C NMR (75 MHz, CDCl3): d 169.9, 161.7, 154.4, 131.4, 126.1, 125.4, 111.5,
107.6, 103.0, 76.2, 67.2, 64.0, 61.4, 60.2, 55.7, 50.0, 46.3, 28.8, 27.9, 24.8, 22.5; MS
(ESI): m=z 318 [MþH]þ. Anal. calcd. for C18H23NO4: C, 68.12; H, 7.30; N, 4.41;
O, 20.16. Found: C, 68.71; H, 7.90; N, 4.39.
ACKNOWLEDGMENTS
This research project was supported by Department of Science and
Technology, New Delhi, India, in the form of a grant. Ritesh, Maloy, and Sankalan
thank the Council of Scientific and Industrial Research for research fellowships. This
is CDRI Communication No. 7345.
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