Nucleosides and Nucleotides p. 957 - 968 (1998)
Update date:2022-08-12
Topics:
Dessolin
Vlieghe
Bouygues
Medou
Quelever
Camplo
Chermann
Kraus
As far as linear N-Boc-polyamines conjugates elicited remarkable anti- HIV activity, the synthesis and anti-HIV properties of cyclic N-Boc- polyamines conjugates such as tetraazamacro-cycle-nucleoside were studied. These new conjugates include an ester linkage between the two moieties. They were synthesized using Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate coupling reagent, in the case of N-alkyl polyazamacrocycle derivatives, or through direct condensation of the acyl chloride derivative with nucleoside in the case of Nacyl polyazamacrocycle compounds. None of the new conjugates presented anti-HIV activity greater than that of the corresponding parent nucleosides.
View MoreZibo Fuxi'er Chemical Co.,Ltd (Shanxian Fuxi'er Chemical Co.,Ltd)
Contact:+86-533-2091422
Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
guide(suzhou) fine materials co. ltd
Contact:0512-80972173
Address:21st Building, No.369 Lushan Rd, New District Suzhou China 215129
Naturalin Bio-Resource Co., Ltd
website:http://www.naturalin.com
Contact:+86-0731-84430651
Address:B1-402, Lu-Valley Enterprise Square.No.27 Wenxuan Road. Lu-Valley Hi-Tech District.
Tianjin Jingye Fine Chemicals Co., Ltd.
Contact:+86-15722078107; +86-22-26911407
Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
website:http://www.amadischem.com
Contact:86-571-89925085
Address:Watts Cosine.No.166.Xiangmao Road.
Doi:10.1107/S0108270106018038
(2006)Doi:10.1021/acs.joc.6b00670
(2016)Doi:10.1016/0584-8539(90)80172-U
(1990)Doi:10.1016/j.ejmech.2021.113799
(2021)Doi:10.1021/es034679t
(2004)Doi:10.1021/ja1067349
(2010)