ACS Medicinal Chemistry Letters p. 683 - 688 (2015)
Update date:2022-08-25
Topics:
Lim, Jongwon
Altman, Michael D.
Baker, James
Brubaker, Jason D.
Chen, Hongmin
Chen, Yiping
Fischmann, Thierry
Gibeau, Craig
Kleinschek, Melanie A.
Leccese, Erica
Lesburg, Charles
Maclean, John K. F.
Moy, Lily Y.
Mulrooney, Erin F.
Presland, Jeremy
Rakhilina, Larissa
Smith, Graham F.
Steinhuebel, Dietrich
Yang, Ruojing
Interleukin-1 receptor associated kinase 4 (IRAK4) is an essential signal transducer downstream of the IL-1R and TLR superfamily, and selective inhibition of the kinase activity of the protein represents an attractive target for the treatment of inflammat
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