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ChemComm
Page 4 of 4
DOI: 10.1039/C7CC02555F
COMMUNICATION
Journal Name
way of designing fluorescent probes for complicated and
dynamic living cell subcellular imaging and detection.
We thank the Natural Science Foundation of China
(No.51573097), the Natural Science Foundation of Guangdong
Province (No. S2013010013056), Nanshan District Key lab for
Biopolymers and safety evaluation (No. KC2014ZDZJ0001A)
and
Postdoctoral
Science
Foundation
of
China
(No.2016M592533) for financial support. We also thank Qin-jie
Long for assistance with the schematic drawings.
Notes and references
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Fig. 4 Analysis of the cellular endocytosis mechanism and photo-
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sucrose and genistein. (*p
< 0.05, t-test). (C) Photo-stability
,
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excitation at 543 nm (circles) from 0 to 30 min. I0 is the initial
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time interval.
PU-1000 for 48 h, suggesting very low cytotoxicity of the
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In conclusion,
a
novel linear fluorescent block
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polyurethane copolymer carrying two different polymer blocks
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block molecular structure that enhances cellular uptake and
facilitate the specificity binding to the dynamic microfilaments.
Visualization of subcellular microfilament systems is achieved
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The TPE-PU nanoparticles are endocytosed through clathrin-
and caveolae-independent energy-dependent pathway. As the
fluorescence properties and the subcellular microfilaments
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4 | J. Name., 2012, 00, 1-3
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