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CCDC 1881635 contains the supplementary crystallographic
bridge Crystallographic Data Centre, 12 Union Road,
Cambridge CB2 1EZ, UK; fax: +44 1223 336033.
1
(
381.
3) For selected examples, see: (a) Li, C.; Zhang, H. H.; Fan, T.;
Shen, Y.; Wu, Q.; Shi, F. Brønsted Acid-Catalyzed Regioselective
Reactions of 2-Indolylmethanols with Cyclic Enaminone and
Anhydride leading to C3-functionalized Indole Derivatives. Org.
Biomol. Chem. 2016, 14, 6932−6936. (b) He, Y. Y.; Sun, X. X.; Li, G.
H.; Mei, G. J.; Shi, F. Substrate-Controlled Regioselective Arylations
of 2-Indolylmethanols with Indoles: Synthesis of Bis(indolyl)methane
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AUTHOR INFORMATION
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*
*
(
c) Zhang, H. H.; Wang, C. S.; Li, C.; Mei, G. J.; Li, Y. X.; Shi, F.
Design and Enantioselective Construction of Axially Chiral Naphthyl-
Indole Skeletons. Angew. Chem., Int. Ed. 2017, 56, 116−121. (d) Hu,
C.; Hong, G.; He, Y. C.; Zhou, C.; Kozlowski, M. C.; Wang, L. M.
Lewis Acid-Controlled Regioselective Phosphorylation of 2-Indolyl-
methanols with Diarylphosphine Oxides: Synthesis of Highly
Substituted Indoles. J. Org. Chem. 2018, 83, 4739−4753. (e) Chen,
L.; Zou, Y. X.; Fang, X. Y.; Wu, J.; Sun, X. H. Brønsted Acid-catalysed
Regiodivergent Phosphorylation of 2-Indolylmethanols to Synthesize
Benzylic Site or C3-Phosphorylated Indole Derivatives. Org. Biomol.
Chem. 2018, 16, 7417−7424.
ORCID
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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We gratefully acknowledge the National Natural Science
Foundation of China (Nos. 21772138 and 21672157), the
project of scientific and technologic infrastructure of Suzhou
(4) Zhou, Y.; Cao, W. B.; Zhang, L. L.; Xu, X. P.; Ji, S. J. Ag(I)-
Promoted Dehydroxylation and Site-Selective 1,7-Disulfonylation of
Diaryl(1H-indol-2-yl)methanols. J. Org. Chem. 2018, 83, 6056−6065.
(
SZS201708), and PAPD. We thank Bei-Bei Liu in this group
for reproducing the result of 3e, 3f, 3h, 3o, and 3t.
(5) (a) Deng, X.; Liang, K. J.; Tong, X. G.; Ding, M.; Li, D. S.; Xia,
C. F. Copper-Catalyzed Radical Cyclization to Access 3-Hydrox-
ypyrroloindoline: Biomimetic Synthesis of Protubonine A. Org. Lett.
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