Uncommon reaction of 2-bromomethyl-1,3-thiaselenole with pyridine and its derivatives

Article abstract of DOI:10.1134/S1070428017110148

Regioselective reaction of 2-bromomethyl-1,3-thiaselenole with pyridine and its derivatives is followed by rearrangement with ring expansion and the formation of a bond between a nitrogen atom and a carbon in the position 2. A set of derivatives of 2,3-dihydro-1,4-thiaselenine was obtained, substituted in the position 2 by a pyridinium residue functionalized by pharmacophoric groups.