Monatshefte fur Chemie p. 1213 - 1216 (1982)
Update date:2022-08-17
Topics:
Haeusler, Johannes
Meldrum's acid (2) is acylated by diketen affording the acyl Meldrum's acid 3.In aqueous bicarbonate its 3-oxogroup is selectively reduced by sodium tetrahydroborate giving the alcohol 4, which readily undergoes cyclization in refluxing dioxane leading to the title pyrone 7.Under identical conditions 3 produces the pyrone 6 with the pyrone carboxylic acid 5 as intermediate. - Keywords: Acyl Meldrum's acid; Ring closure; Selective reduction
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