THE SYNTHSIS OF OLIGODEOXYPYRIMIDINES ON A POLYMER SUPPORT

DOI: 10.1016/S0040-4039(00)71455-9

Source and publish data:

Tetrahedron Letters p. 719 - 722 (1980)

Update date:2022-08-17

Topics:

Authors:

Matteucci, M. D.

Caruthers, M. H.

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Article abstract of DOI:10.1016/S0040-4039(00)71455-9

A polymer supported method for synthesizing deoxypolynucleotides is described.Two nonanucleotides were synthesized.Yields exceeding 90percent were obtained for each condensation.The time per nucleotide addition was four hours.

Full text of DOI:10.1016/S0040-4039(00)71455-9

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