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Furo[2,3-c]pyridine-2-carboxylic acid

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Name

Furo[2,3-c]pyridine-2-carboxylic acid

EINECS N/A
CAS No. 112372-15-3 Density 1.455 g/cm3
PSA 63.33000 LogP 1.52600
Solubility N/A Melting Point >320℃
Formula C8H5NO3 Boiling Point 352.997 °C at 760 mmHg
Molecular Weight 163.133 Flash Point 167.287 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 112372-15-3 (Furo[2,3-c]pyridine-2-carboxylic acid) Hazard Symbols N/A
Synonyms

QC-5056;furo[2,3-c]pyridin-2-carboxylic acid;furo<2,3-c>pyridine-2-carboxylic acid;

Article Data 9

Furo[2,3-c]pyridine-2-carboxylic acid Specification

The Furo[2, 3-c]pyridine-2-carboxylic acid has CAS registry number 112372-15-3. This chemical's molecular formula is C8H5NO3 and molecular weight is 163.132. What's more, its systematic name is Furo[2, 3-c]pyridine-2-carboxylic acid.

Physical properties about Furo[2, 3-c]pyridine-2-carboxylic acid are: (1)ACD/LogP: 0.50; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2; (4)ACD/LogD (pH 7.4): -2; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 63.33 Å2; (13)Index of Refraction: 1.661; (14)Molar Refractivity: 41.416 cm3; (15)Molar Volume: 112.097 cm3; (16)Polarizability: 16.419×10-24 cm3; (17)Surface Tension: 67.546 dyne/cm; (18)Density: 1.455 g/cm3; (19)Flash Point: 167.287 °C; (20)Enthalpy of Vaporization: 63.091 kJ/mol; (21)Boiling Point: 352.997 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25 °C.

Preparation of Furo[2, 3-c]pyridine-2-carboxylic acid: this chemical is prepared by Furo[2, 3-c]pyridine-2-carbonitrile by heating. The reaction needs reagent KOH and solvent Ethanol. The reaction time is 2 hours. The yield is about 95 %.

The Furo[2, 3-c]pyridine-2-carboxylic acid can be prepared by Furo[2, 3-c]pyridine-2-carbonitrile.

Uses of Furo[2, 3-c]pyridine-2-carboxylic acid: it is used to produce other chemicals. For example, it is used to produce Furo[2, 3-c]pyridine-2-carboxylic acid ethyl ester by heating. The reaction needs reagent H2SO4. The reaction time is 15 hours. The yield is about 78 %.

The Furo[2, 3-c]pyridine-2-carboxylic acid can react with Ethanol to get Furo[2, 3-c]pyridine-2-carboxylic acid ethyl ester.

You can still convert the following datas into molecular structure:
(1) SMILES: OC(=O)c1cc2ccncc2o1
(2) InChI: InChI=1/C8H5NO3/c10-8(11)6-3-5-1-2-9-4-7(5)12-6/h1-4H,(H,10,11)
(3) InChIKey: WMPIDXCJMDIDQY-UHFFFAOYAF

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