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Name	Gludiase	EINECS	N/A
CAS No.	1492-02-0	Density	1.344g/cm³
PSA	108.57000	LogP	3.79020
Solubility	N/A	Melting Point	163°
Formula	C12H15 N3 O2 S2	Boiling Point	449.4°Cat760mmHg
Molecular Weight	297.402	Flash Point	225.6°C
Transport Information	N/A	Appearance	N/A
Safety	Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. When heated to decomposition it emits toxic fumes of SO_x and NO_x.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Benzenesulfonamide,N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)- (6CI,7CI,8CI); 2-Benzenesulfonamido-5-tert-butyl-1,3,4-thiadiazole;2-Phenylsulfonamido-5-tert-butyl-1,3,4-thiadiazole; Desaglybuzole; Gludiase;Glybuzol; Glybuzole; N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide;RP 7891; TH 1395	Article Data	3

Gludiase Chemical Properties

IUPAC Name: N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Synonyms of Gludiase (CAS NO.1492-02-0) : Benzenesulfonamide, N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]- ; N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide ; Sulfamidothiodiazol
InChI:InChI=1/C12H15N3O2S2/c1-12(2,3)10-13-14-11(18-10)15-19(16,17)9-7-5-4-6-8-9/h4-8H,1-3H3,(H,14,15)
CAS NO:1492-02-0
Molecular Formula:C₁₂H₁₅N₃O₂S₂
Molecular Weight :297.3964
Molecular Structure :
EINECS: 216-081-2
Index of Refraction:1.605
Surface Tension: 60.2 dyne/cm
Density: 1.344 g/cm³
Flash Point: 225.6 °C
Enthalpy of Vaporization: 70.8 kJ/mol
Boiling Point: 449.4 °C at 760 mmHg
Vapour Pressure: 2.88E-08 mmHg at 25°C

Gludiase Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	235mg/kg (235mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
mouse	LD50	intravenous	193mg/kg (193mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
mouse	LD50	oral	550mg/kg (550mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA ENDOCRINE: HYPOGLYCEMIA	Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 131, 1969.
mouse	LD50	subcutaneous	248mg/kg (248mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rabbit	LD50	intraperitoneal	300mg/kg (300mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rabbit	LD50	intravenous	118mg/kg (118mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rabbit	LD50	oral	967mg/kg (967mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rat	LD50	intraperitoneal	219mg/kg (219mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rat	LD50	oral	500mg/kg (500mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.
rat	LD50	subcutaneous	310mg/kg (310mg/kg)		Yamaguchi Igaku. Yamaguchi Medicine. Vol. 18, Pg. 21, 1969.

Gludiase Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. When Gludiase (CAS NO.1492-02-0) is heated to decomposition, it emits toxic fumes of SO_x and NO_x.

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