Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Guanosine 5'-monophosphate disodium salt
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

Guanosine 5'-monophosphate disodium salt

 EINECS 226-914-1
CAS No. 5550-12-9 Density N/A
PSA 221.51000 LogP -1.11210
Solubility >50 g/L in water Melting Point 300 °C
Formula C10H12N5Na2O8P Boiling Point 890.2oC at 760 mmHg
Molecular Weight 407.187 Flash Point 492.2oC
Transport Information N/A Appearance White crystalline powder
Safety 22-24/25-36/37/39-27-26 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 5550-12-9 (Guanosine 5'-monophosphate disodium salt) Hazard Symbols IrritantXi
Synonyms

5'-Guanylicacid, disodium salt (7CI,8CI,9CI);5'-GMP disodium salt;Disodium 5'-GMP;Disodium 5'-guanylate;Disodium GMP;Disodium guanosine 5'-monophosphate;Disodium guanosine 5'-phosphate;Disodium guanylate;E 627;GMP disodium salt;GMP sodium salt;Guanosine 5'-monophosphate disodium salt;Guanosine5'-phosphate disodium salt;Guanylic acid sodium salt;NSC 20265;Sodium5'-guanylate;Sodium GMP;Sodium guanosine 5'-monophosphate;Sodium guanylate;

Article Data 3

Guanosine 5'-monophosphate disodium salt Synthetic route

guanosine-5'-phosphoro-(2-aminoimidazole)

A

7720-39-0

1H-imidazol-2-amine

B

5550-12-9

guanosine 5'-monophosphate disodium

Conditions
ConditionsYield
With trimethyl phosphite; water; sodium chloride; magnesium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid In water-d2 at 25℃; Kinetics;
80242-42-8

guanosine-5'-(2-methylimidazol-1-yl phosphate)

A

693-98-1

2-methylimidazole

B

5550-12-9

guanosine 5'-monophosphate disodium

Conditions
ConditionsYield
With trimethyl phosphite; water; sodium chloride; magnesium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid In water-d2 at 25℃; Kinetics;

C10H14N6O10P2(2-)*2Na(1+)

5550-12-9

guanosine 5'-monophosphate disodium

Conditions
ConditionsYield
With water; zinc(II) cation pH=5.5;
5550-12-9

guanosine 5'-monophosphate disodium

85-32-5

5'-guanosine monophosphate

Conditions
ConditionsYield
With Dowex 50W×8 resin In water at 20℃; for 0.5h;99%
With Dowex 50WX-8 200 mesh, H+
288-32-4

1H-imidazole

5550-12-9

guanosine 5'-monophosphate disodium

121-44-8

triethylamine

triethylammonium guanosin-5'-yl monophosphate P-imidazolide

Conditions
ConditionsYield
With 2,2'-dipyridyldisulphide; triphenylphosphine In N,N-dimethyl-formamide at 20℃;90%
5550-12-9

guanosine 5'-monophosphate disodium

874-98-6

1-bromomethyl-3-methoxybenzene

((2R,3S,4R,5R)-5-(2-amino-7-(3-methoxybenzyl)-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 24h;81%
15663-27-1

cisplatin

5550-12-9

guanosine 5'-monophosphate disodium

cis-[Pt(NH3)2(5'-guanosine monophosphateNa2)2]Cl2

Conditions
ConditionsYield
In water mixture is heated at 50°C for about 3-5 h with stirring; the clear soln. is left overnight at room temp.;; concn. under vacuum; pptn. with acetone, then with ether; white ppt. isfiltered off, washed with acetone, then with ether and dried in air;;75%
In water stirring Pt-complex with 2 equiv. of ligand (room temp., 3 h, in dark);
5550-12-9

guanosine 5'-monophosphate disodium

622-95-7

4-chlorobenzyl bromide

((2R,3S,4R,5R)-5-(2-amino-7-(4-chlorobenzyl)-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 24h;75%
5550-12-9

guanosine 5'-monophosphate disodium

89-92-9

2-methylbenzyl bromide

((2R,3S,4R,5R)-5-(2-amino-7-(2-methylbenzyl)-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 24h;71%
5550-12-9

guanosine 5'-monophosphate disodium

100-39-0

benzyl bromide

((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 24h;70%

Guanosine 5'-monophosphate disodium salt Chemical Properties

IUPAC Name:disodium [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Molecular Formula:C10H12N5Na2O8P
Molecular Weight:407.184281 g/mol
Appearance:White crystalline powder
Melting Point:300 °C 
Solubility:slightly soluble in ethanol, acetone and ether
storage temp.:2-8 °C
Water Solubility:>50 g/L
FEMA:3668
EINECS:226-914-1
Synonyms of GUANYLIC ACID SODIUM SALT(5550-12-9):
GMP-5;5’-gmpdisodiumsalt;disodium5’-gmp;disodiumgmp;gmpsodiumsalt;sodium5’-guanylate;sodiumgmp;sodiumguanosine5’-monophosphate;Guanosine 5'-monophosphate disodium salt
Categories of GUANYLIC ACID SODIUM SALT(5550-12-9):
Pharmaceutical Intermediates;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs;Nucleic acids

Guanosine 5'-monophosphate disodium salt Uses

GUANYLIC ACID SODIUM SALT(5550-12-9) is mainly used as a condiment.

Guanosine 5'-monophosphate disodium salt Toxicity Data With Reference

1.   

cyt-ham:fbr 1 g/L

   FCTOD7    Food and Chemical Toxicology. 22 (1984),623.
2.   

ipr-rat LD50:3880 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
3.   

scu-rat LD50:3400 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
4.   

ivn-rat LD50:2720 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
5.   

orl-mus LD50:15 g/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
6.   

ipr-mus LD50:5010 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
7.   

scu-mus LD50:5050 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)
8.   

ivn-mus LD50:3580 mg/kg

   AJINO*    Ajinomoto Co., Inc. (9W. 57th St., Suite 4625, New York, NY 10019)

Guanosine 5'-monophosphate disodium salt Consensus Reports

Reported in EPA TSCA Inventory.

Guanosine 5'-monophosphate disodium salt Safety Profile

Safety Information of GUANYLIC ACID SODIUM SALT(5550-12-9):
Hazard Codes:Xi
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements:22-24/25-36/37/39-27-26
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
27:Take off immediately all contaminated clothing
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany:2
RTECS:MF9290000
Moderately toxic by intraperitoneal, subcutaneous, and intravenous routes. Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of POx, NOx, and Na2O.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 5550-12-9