Reported in EPA TSCA Inventory.

The IUPAC name of this chemical is 2,2,3,3,4,4,4-heptafluorobutanoic acid. With the CAS registry number 375-22-4 and EINECS registry number 206-786-3, it is also named as Heptafluorobutyric acid. In addition, the molecular formula is C₄HF₇O₂ and the molecular weight is 214.04. What's more, it is a kind of clear colorless to faintly yellow liquid and belongs to the classes of Pharmaceutical Intermediates; Analytical Chemistry; Ion-Pair Reagents for HPLC; LC/MS Ion-Pair Reagents for Basic Samples; Acylation (GC Derivatizing Reagents); GC Derivatizing Reagents.

Physical properties about this chemical are: (1)ACD/LogP: 3.93; (2)ACD/LogD (pH 5.5): 0.2; (3)ACD/LogD (pH 7.4): 0.18; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 2; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 26.3 Å²; (12)Index of Refraction: 1.291; (13)Molar Refractivity: 23.18 cm³; (14)Molar Volume: 127.4 cm³; (15)Polarizability: 9.19 ×10^-24cm³; (16)Surface Tension: 18.6 dyne/cm; (17)Density: 1.679 g/cm³; (18)Flash Point: 18 °C; (19)Enthalpy of Vaporization: 39.54 kJ/mol; (20)Boiling Point: 120.2 °C at 760 mmHg; (21)Vapour Pressure: 9.8 mmHg at 25°C.

Preparation of Heptafluorobutyric acid: it can be prepared by 1,1,1,2,2,3,3,4,4-nonafluoro-4-iodo-butane. This reaction will need reagents lipoxygenase, 1/30 M aq. Na₂HPO₄/KH₂PO₄ and 2-octyne. The yield is about 83% at reaction temperature of 25-30 °C.

Uses of Heptafluorobutyric acid: It can be used an ion pair reagent for reverse-phase HPLC. And it is used in the sequencing, synthesis, and solubilizing of proteins and peptides. In addition, it can be used to get heptafluorobutyryl fluoride. This reaction will need reagents FAR and NaF. The reaction time is 15 minutes at reaction temperature of -78 °C. The yield is about 84%.

When you are using this chemical, please be cautious about it as the following:
This chemical can cause severe burns. During using it, wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. And in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.).

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(C(F)(F)C(=O)O)C(F)(F)F
(2)InChI: InChI=1/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)
(3)InChIKey: YPJUNDFVDDCYIH-UHFFFAOYAI

The toxicity data is as follows: