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Hydroxyzine monohydrochloride

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Name

Hydroxyzine monohydrochloride

EINECS N/A
CAS No. 1244-76-4 Density g/cm3
PSA 35.94000 LogP 3.73370
Solubility N/A Melting Point N/A
Formula C21H27 Cl N2 O2 . Cl H Boiling Point 499.2°Cat760mmHg
Molecular Weight 411.372 Flash Point 255.7°C
Transport Information N/A Appearance N/A
Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. Used as a tranquilizer. Risk Codes N/A
Molecular Structure Molecular Structure of 1244-76-4 (2-[2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride) Hazard Symbols N/A
Synonyms

Ethanol,2-[2-[4-(p-chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]-, monohydrochloride (8CI); Ethanol,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-,monohydrochloride (9CI); Hydroxyzine monohydrochloride

 

Hydroxyzine monohydrochloride Chemical Properties

IUPAC Name: 2-[2-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride
The MF of Hydroxyzine monohydrochloride (CAS NO.1244-76-4) is C21H28Cl2N2O2.

                    
The MW of Hydroxyzine monohydrochloride (CAS NO.1244-76-4) is 411.36522.
Synonyms of Hydroxyzine monohydrochloride (CAS NO.1244-76-4): 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]ethanol hydrochloride ; Hydroxyzine monohydrochloride
Flash Point: 255.7 °C
Boiling Point: 499.2 °C
EINECS: 214-989-3

Hydroxyzine monohydrochloride Uses

  Hydroxyzine monohydrochloride (CAS NO.1244-76-4) is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Hydroxyzine monohydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:690 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),621.
2.    

ipr-rat LD50:126 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
3.    

orl-mus LD50:515 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 127 (1959),318.
4.    

ipr-mus LD50:137 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),621.
5.    

ivn-mus LD50:56 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),621.

Hydroxyzine monohydrochloride Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. Used as a tranquilizer.

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