Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	Indole-2-carboxylic acid	EINECS	216-030-4
CAS No.	1477-50-5	Density	1.408 g/cm³
PSA	53.09000	LogP	1.86610
Solubility	N/A	Melting Point	202-206 °C(lit.)
Formula	C₉H₇NO₂	Boiling Point	419.6 °C at 760 mmHg
Molecular Weight	161.16	Flash Point	207.6 °C
Transport Information	N/A	Appearance	Off-white crystal powder
Safety	22-24/25	Risk Codes	36/37/38-21/22
Molecular Structure		Hazard Symbols	Xi,Xn
Synonyms	1H-Indole-2-carboxylic acid (9CI);1H-indole-2-carboxylate;2-Carboxyindole;2-Indole carboxylic acid,methyl ester;2-Indolecarboxylic acid:Indole-2-carboxylic acid;indole-2-formic acid;Indole-2-carboxlicacid;1H-2-Indolecarboxylic acid;	Article Data	98

Indole-2-carboxylic acid Synthetic route

: 3770-50-1
2-carbethoxyindole

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With potassium hydroxide In water at 120℃; for 0.5h;	99.9%
With sodium hydroxide In ethanol; water at 70℃; for 2h;	97%
With sodium hydroxide at 200℃; for 0.0166667h; Irradiation; microwave;	94%

: 40899-93-2
1-(phenylsulfonyl)-1H-indole-2-carboxylic acid

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With sodium t-butanolate In 1,4-dioxane at 80℃; for 3h; Inert atmosphere;	98%

: 5461-32-5
o-nitrophenylpyruvic acid

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With sodium dithionite In 1,4-dioxane; water for 3h; Reflux;	96%
With sodium hydroxide; sodium dithionite

: 16851-56-2
indolin-2-yl carboxylic acid

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With potassium tert-butylate In decane at 150℃; for 36h; Inert atmosphere; Schlenk technique;	96%
With carbon dioxide; DBN; Eosin Y In dimethyl sulfoxide at 25 - 30℃; for 48h; Irradiation;	91%
With 4-tert-Butylcatechol; oxygen In water at 20℃; for 20h; Green chemistry;	80%
With perylene diimide covalent immobilized to SiO2 nanospheres; air In N,N-dimethyl acetamide at 20℃; UV-irradiation;	67%
With oxygen at 80℃; under 760.051 Torr; for 6h; Catalytic behavior; Green chemistry; chemoselective reaction;

: (4Z)-4-[(2-bromophenyl)methylene]-2-phenyl-1,3-oxazole-5-one

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With methanol; potassium carbonate; copper(I) bromide In N,N-dimethyl-formamide at 20 - 120℃; Reagent/catalyst; Temperature; Solvent;	95%

: 52900-69-3, 77435-90-6, 82301-55-1
(Z)-2-phenyl-4-(2-chlorobenzylidene)-(4H)-1,3-oxazol-5-one

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With methanol; copper; sodium carbonate In toluene at 20 - 120℃;	90%

: 127-17-3
2-oxo-propionic acid

: 615-36-1
2-bromoaniline

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With potassium phosphate; bis(N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)palladium(0) In 1,4-dioxane at 100℃; for 10h; Inert atmosphere;	89%

: 124-38-9
carbon dioxide

: 139409-34-0
2-bromo-1H-indole

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
Stage #1: 2-bromo-1H-indole With isopropylmagnesium chloride In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: With n-butyllithium In tetrahydrofuran; hexane at -20℃; for 0.5h; Stage #3: carbon dioxide In tetrahydrofuran; hexane at -20℃; for 0.5h;	85%

: n-butyl 1-(pyrimidin-2-yl)-1H-indole-2-carboxylate

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With sodium ethanolate In ethanol; dimethyl sulfoxide at 100℃; for 11h; regioselective reaction;	84%

: 615-43-0
2-iodophenylamine

: 127-17-3
2-oxo-propionic acid

: 1477-50-5
Indole-2-carboxylic acid

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate In N,N-dimethyl-formamide at 105℃;	82%
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate In N,N-dimethyl-formamide at 105℃; Inert atmosphere; regioselective reaction;	82%

Indole-2-carboxylic acid Chemical Properties

Product Name: Indole-2-carboxylic acid (CAS NO.1477-50-5)

Molecular Formula: C₉H₇NO₂
Molecular Weight: 161.16g/mol
Mol File: 1477-50-5.mol
EINECS: 216-030-4
Melting Point: 202-206 °C(lit.)
Boiling point: 419.6 °C at 760 mmHg
Flash Point: 207.6 °C
Density: 1.408 g/cm³
Index of Refraction: 1.725
Molar Refractivity: 45.45 cm³
Molar Volume: 114.4 cm³
Surface Tension: 71.6 dyne/cm
Enthalpy of Vaporization: 70.99 kJ/mol
Vapour Pressure: 8.6E-08 mmHg at 25°C
XLogP3-AA: 2.3
H-Bond Donor: 2
H-Bond Acceptor: 2
Structure Descriptors of Indole-2-carboxylic acid (CAS NO.1477-50-5):
IUPAC Name: 1H-indole-2-carboxylic acid
Canonical SMILES: C1=CC=C2C(=C1)C=C(N2)C(=O)O
InChI: InChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12)
InChIKey: HCUARRIEZVDMPT-UHFFFAOYSA-N
Product Categories: Indole/indoline/oxindole; indole derivative; Indole and Indoline; Indoles and derivatives; Carboxylic Acids; Pyrroles & Indoles; Indole; Organic acids; Amino Acids 13C, 2H, 15N; Indoles; Simple Indoles; Amino Acids & Derivatives; Indole Derivatives; Carboxylic Acids; Pyrroles & Indoles

Indole-2-carboxylic acid Safety Profile

Safety Information of Indole-2-carboxylic acid (CAS NO.1477-50-5):
Hazard Codes: Xn Harmful ,Xi Irritant
Risk Statements: 36/37/38-21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21:Harmful by inhalation and in contact with skin.
Safety Statements: 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: NK7882812
Hazard Note: Irritant
HazardClass: IRRITANT
HS Code: 29339990

Indole-2-carboxylic acid Specification

Indole-2-carboxylic acid , its CAS NO. is 1477-50-5, the synonyms are 2-Carboxyindole ; 2-Indolecarboxylic acid ; 1H-Indole-2-carboxylic acid (9CI) .

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1477-50-5