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| Name |
Insidon dihydrochloride |
EINECS | N/A |
| CAS No. | 909-39-7 | Density | 1.129g/cm3 |
| PSA | 29.95000 | LogP | 4.85330 |
| Solubility | N/A | Melting Point |
210° (FR M209); mp 228-230° (DE 1133729) |
| Formula | C23H29 N3 O . 2 Cl H | Boiling Point | 555.1°Cat760mmHg |
| Molecular Weight | 436.47 | Flash Point | 290.5°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | A poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence. When heated to decomposition it emits very toxic fumes of NOx and HCl. | Risk Codes | 22-50/53 |
| Molecular Structure |
|
Hazard Symbols |
 
|
| Synonyms |
1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, dihydrochloride (7CI,8CI,9CI);5H-Dibenz[b,f]azepine, 1-piperazineethanol deriv.;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride;5-[g-(b-Hydroxyethylpiperazino)propyl]-5H-dibenzo[b,f]azepinedihydrochloride; Dinsidon; G 33040; Insidon; Insidone; Nisidana; Opipramolhydrochloride; Pramolan |
Insidon dihydrochloride Chemical Properties
IUPAC Name: 2-[4-(3-Benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol dihydrochloride
Synonyms of Insidon dihydrochloride (CAS NO.909-39-7) : 1-Piperazineethanol, 4-(3-(5H-dibenz(b,f)azepin-5-yl)propyl)-, dihydrochloride ; 4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanol dihydrochloride ; Insidon (TN) ; Opipramol dihydrochloride
Product Categories: Dopamine receptor
CAS NO:909-39-7
Molecular Formula:C23H31Cl2N3O
Molecular Weight :436.41774
Molecular Structure :
EINECS: 213-000-2
Flash Point: 290.5 °C
Enthalpy of Vaporization: 88 kJ/mol
Boiling Point: 555.1 °C at 760 mmHg
Vapour Pressure: 3.72E-13 mmHg at 25°C
Solubility : H2O: ~24 mg/mL
Appearance: Insidon dihydrochloride (CAS NO.909-39-7) is yellow solid.
Insidon dihydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| human | TDLo | oral | 36mg/kg/25D-C (36mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of Psychiatry. Vol. 119, Pg. 465, 1962. |
| mouse | LD50 | intraperitoneal | 120mg/kg (120mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| mouse | LD50 | intravenous | 45mg/kg (45mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| mouse | LD50 | oral | 443mg/kg (443mg/kg) | Rassegna di Studi Psichiatrici. Review of Psychiatric Studies. Vol. 52, Pg. 204, 1963. | |
| mouse | LD50 | subcutaneous | 315mg/kg (315mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| rabbit | LD50 | intravenous | 11mg/kg (11mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| rat | LD50 | intraperitoneal | 95mg/kg (95mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| rat | LD50 | intravenous | 32mg/kg (32mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. | |
| rat | LD50 | oral | 900mg/kg (900mg/kg) | Drugs in Japan Vol. 6, Pg. 161, 1982. | |
| rat | LD50 | subcutaneous | 497mg/kg (497mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 148, Pg. 560, 1964. |
Insidon dihydrochloride Safety Profile
A poison by intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: somnolence. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Hazard Codes
Xn,
N
Risk Statements 22-50/53
R22:Harmful if swallowed.
R50/53: Insidon dihydrochloride (CAS NO.909-39-7) is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements 60-61
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany 3
RTECS TL9100000
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